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Generated: December 11, 2018

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CLINICAL TRIALS PROFILE FOR LEUPROLIDE ACETATE

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Clinical Trials for Leuprolide Acetate

Trial ID Title Status Sponsor Phase Summary
NCT00003124 Hormone Therapy Plus Radiation Therapy in Treating Patients With Prostate Cancer Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Hormone therapy using leuprolide and flutamide may fight prostate cancer by reducing the production of androgens. Combining radiation therapy with hormone therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of hormone therapy plus radiation therapy in treating patients with prostate cancer.
NCT00003124 Hormone Therapy Plus Radiation Therapy in Treating Patients With Prostate Cancer Completed Herbert Irving Comprehensive Cancer Center Phase 2 RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Hormone therapy using leuprolide and flutamide may fight prostate cancer by reducing the production of androgens. Combining radiation therapy with hormone therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of hormone therapy plus radiation therapy in treating patients with prostate cancer.
NCT00003653 Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer Completed National Cancer Institute (NCI) Phase 3 RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Hormone therapy may fight prostate cancer by reducing the production of androgens. It is not yet known which androgen suppression regimen is more effective for prostate cancer. PURPOSE: This randomized phase III trial is studying two hormone therapy regimens and comparing them to see how well they work in treating patients with rising PSA levels following radiation therapy for prostate cancer.
NCT00003653 Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer Completed Southwest Oncology Group Phase 3 RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Hormone therapy may fight prostate cancer by reducing the production of androgens. It is not yet known which androgen suppression regimen is more effective for prostate cancer. PURPOSE: This randomized phase III trial is studying two hormone therapy regimens and comparing them to see how well they work in treating patients with rising PSA levels following radiation therapy for prostate cancer.
NCT00003653 Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer Completed NCIC Clinical Trials Group Phase 3 RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Hormone therapy may fight prostate cancer by reducing the production of androgens. It is not yet known which androgen suppression regimen is more effective for prostate cancer. PURPOSE: This randomized phase III trial is studying two hormone therapy regimens and comparing them to see how well they work in treating patients with rising PSA levels following radiation therapy for prostate cancer.
NCT00004311 Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome Completed Baylor College of Medicine Phase 2 OBJECTIVES: I. Evaluate insulin resistance in thin and obese hyperandrogenic women with polycystic ovarian disease or hyperandrogenism insulin resistance acanthosis nigricans syndrome and in thin and obese controls, using an estimation of tissue sensitivity to insulin. II. Evaluate the effect of androgen suppression with leuprolide acetate and spironolactone on insulin secretion and resistance.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Leuprolide Acetate

Condition Name

Condition Name for Leuprolide Acetate
Intervention Trials
Prostate Cancer 47
Infertility 9
Prostate Adenocarcinoma 7
Stage IV Prostate Cancer 7
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Condition MeSH

Condition MeSH for Leuprolide Acetate
Intervention Trials
Prostatic Neoplasms 62
Adenocarcinoma 14
Infertility 9
Puberty, Precocious 7
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Clinical Trial Locations for Leuprolide Acetate

Trials by Country

Trials by Country for Leuprolide Acetate
Location Trials
United States 485
Canada 45
Italy 13
Japan 11
Belgium 10
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Trials by US State

Trials by US State for Leuprolide Acetate
Location Trials
New York 23
Texas 23
California 22
Michigan 20
Florida 19
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Clinical Trial Progress for Leuprolide Acetate

Clinical Trial Phase

Clinical Trial Phase for Leuprolide Acetate
Clinical Trial Phase Trials
Phase 4 15
Phase 3 26
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for Leuprolide Acetate
Clinical Trial Phase Trials
Completed 50
Recruiting 21
Terminated 11
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Clinical Trial Sponsors for Leuprolide Acetate

Sponsor Name

Sponsor Name for Leuprolide Acetate
Sponsor Trials
National Cancer Institute (NCI) 24
Abbott 6
M.D. Anderson Cancer Center 6
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Sponsor Type

Sponsor Type for Leuprolide Acetate
Sponsor Trials
Other 96
Industry 47
NIH 32
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Serving hundreds of leading biopharmaceutical companies globally:

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