Combining Lesinurad With Allopurinol in Inadequate Responders
Completed
Ardea Biosciences, Inc.
Phase 3
2011-12-01
This study will compare the serum uric acid lowering effects, clinical benefits, and safety
of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who
have had an inadequate response to allopurinol.
Lesinurad Monotherapy in Gout Subjects Intolerant to Xanthine Oxidase Inhibitors
Completed
Ardea Biosciences, Inc.
Phase 3
2012-01-01
This study will assess the serum uric acid lowering effects and safety of lesinurad compared
to placebo in patients who are intolerant or have a contraindication to allopurinol or
febuxostat.
Combining Lesinurad With Allopurinol in Inadequate Responders
Completed
Ardea Biosciences, Inc.
Phase 3
2012-01-01
This study that compare the serum uric acid lowering effects, clinical benefits, and safety
of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who
have had an inadequate response to allopurinol.
Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat
Completed
Ardea Biosciences, Inc.
Phase 3
2012-01-01
This study will compare the serum uric acid lowering effects, clinical benefits, and safety
of lesinurad in combination with febuxostat to febuxostat alone in patients with tophaceaous
gout.
This study will explore the safety, tolerability, and serum uric acid lowering effect of
lesinurad in healthy Japanese males to allow comparison with the Western population.
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