Terbinafine Compared to Griseofulvin in Children With Tinea Capitis
Tinea capitis is a dermatophyte infection of the scalp hair follicles, which occurs
primarily in children. Hair loss, hair breakage, scaling, plus various degrees of erythema,
pustules and pruritus are the primary clinical signs which can be associated with tinea
capitis. The infection is caused by a relatively small group of dermatophytes in the genera
Trichophyton and Microsporum.
Terbinafine hydrochloride is a synthetic allylamine derivative antifungal agent. This study
will evaluate the efficacy and safety of terbinafine in children with tinea capitis.
Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big Toenail
This study is designed to assess the efficacy, safety and tolerability of a topical
formulation of terbinafine solution applied daily in patients with toenail fungus. This
trial will study patients with mild to moderate toenail fungus disease of the big toenail
and their responses to two treatment durations, 24 or 48 weeks.
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