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CLINICAL TRIALS PROFILE FOR INVOKANA

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All Clinical Trials for Invokana

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01877889	A Study to Compare the Pharmacodynamics of Canagliflozin and Dapagliflozin in Healthy Volunteers	Completed	Janssen-Cilag International NV	Phase 1	2013-07-01	The purpose of this study is to compare the pharmacodynamics (ie, how the drug affects the body) of canagliflozin with the pharmacodynamics of dapagliflozin.
NCT01916863	Study to Evaluate the Effect of Single Doses of LX4211 and Canagliflozin on Intestinal Glucose Absorption in Healthy Adult Subjects	Completed	Lexicon Pharmaceuticals	Phase 1	2013-08-01	The purpose of this study is to assess the effect of LX4211 and the comparator drug canagliflozin on intestinal glucose absorption and metabolism after a single dose in healthy subjects in comparison to placebo.
NCT02009488	Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)	Active, not recruiting	Janssen Research & Development, LLC	Phase 1	2014-09-01	The purpose of this study is to assess changes from baseline in insulin sensitivity, hepatic fat content and beta cell function after approximately 24-25 weeks of treatment with canagliflozin compared to placebo in participants with type 2 diabetes mellitus (T2DM) with inadequate glycemic (blood sugar) control on metformin monotherapy or on combination therapy with metformin and a dipeptidyl peptidase-4 (DPP-4) inhibitor.
NCT02243202	Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants	Completed	Janssen Research & Development, LLC	Phase 2	2014-09-01	The purpose of this study is to compare the effects of canagliflozin and phentermine to those of placebo to promote on a change in body weight over a 26 week period.

Clinical Trial Conditions for Invokana

Condition Name

Condition Name for Invokana
Intervention	Trials
Diabetes Mellitus, Type 2	6
Obesity	3
Heart Failure	2
Type 2 Diabetes Mellitus	2

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Condition MeSH

Condition MeSH for Invokana
Intervention	Trials
Diabetes Mellitus	12
Diabetes Mellitus, Type 2	11
Heart Failure	3
Overweight	2

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Clinical Trial Locations for Invokana

Trials by Country

Trials by Country for Invokana
Location	Trials
United States	33
United Kingdom	3
Germany	1
China	1

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Trials by US State

Trials by US State for Invokana
Location	Trials
Texas	3
California	3
Massachusetts	3
Maryland	2
Virginia	2

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Clinical Trial Progress for Invokana

Clinical Trial Phase

Clinical Trial Phase for Invokana
Clinical Trial Phase	Trials
Phase 4	10
Phase 3	2
Phase 2	1

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Clinical Trial Status

Clinical Trial Status for Invokana
Clinical Trial Phase	Trials
Recruiting	9
Not yet recruiting	6
Completed	3

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Clinical Trial Sponsors for Invokana

Sponsor Name

Sponsor Name for Invokana
Sponsor	Trials
Janssen Scientific Affairs, LLC	7
Janssen Research & Development, LLC	3
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	2

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Sponsor Type

Sponsor Type for Invokana
Sponsor	Trials
Other	22
Industry	14
NIH	2

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