CLINICAL TRIALS PROFILE FOR INVERSINE

All Clinical Trials for Inversine

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00262470 ↗	Treatment of Orthostatic Intolerance	Active, not recruiting	National Institutes of Health (NIH)	Phase 1/Phase 2	1997-04-01	This trial is designed to study the effects of various mechanistically unique medications in controlling excessive increases in heart rate with standing and in improving the symptoms of orthostatic intolerance in patients with this disorder.
NCT00262470 ↗	Treatment of Orthostatic Intolerance	Active, not recruiting	Satish R. Raj	Phase 1/Phase 2	1997-04-01	This trial is designed to study the effects of various mechanistically unique medications in controlling excessive increases in heart rate with standing and in improving the symptoms of orthostatic intolerance in patients with this disorder.
NCT00319319 ↗	Nicotinic Receptor Augmentation of SSRI Antidepressants	Completed	Donaghue Medical Research Foundation	Phase 2	2003-01-01	The purpose of this study is to determine whether the nicotinic receptor antagonist mecamylamine hydrochloride (Inversine) can augment SSRI-refractory major depression symptoms, quality of life and cigarette smoking outcomes. A total of n=60 SSRI-refractory patients who are on stable doses of an SSRI are being recruited into this 8-week double-blind, randomized, placebo-controlled trial.

Clinical Trial Conditions for Inversine

Condition Name

Condition Name for Inversine
Intervention	Trials
Pervasive Developmental Disorder	1
Tachycardia	1
Alcohol Dependence	1

Condition MeSH

Condition MeSH for Inversine
Intervention	Trials
Depression	3
Depressive Disorder	3
Disease	2

Clinical Trial Locations for Inversine

Trials by Country

Trials by Country for Inversine
Location	Trials
United States	5

Trials by US State

Trials by US State for Inversine
Location	Trials
Connecticut	2
Ohio	1
Massachusetts	1
Tennessee	1

Clinical Trial Progress for Inversine

Clinical Trial Phase

Clinical Trial Phase for Inversine
Clinical Trial Phase	Trials
Phase 3	1
Phase 2	2
Phase 1/Phase 2	1

Clinical Trial Status

Clinical Trial Status for Inversine
Clinical Trial Phase	Trials
Completed	5
Active, not recruiting	1

Clinical Trial Sponsors for Inversine

Sponsor Name

Sponsor Name for Inversine
Sponsor	Trials
Yale University	2
National Alliance for Research on Schizophrenia and Depression	2
Targacept Inc.	1

Sponsor Type

Sponsor Type for Inversine
Sponsor	Trials
Other	10
NIH	1
Industry	1