Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]
Recruiting
Pfizer
2008-01-04
The purpose of this registry is to obtain a general view as regards efficacy, tolerability
and safety issues of the Torisel®, Sutent®, and/or Inlyta® therapies in patients with
advanced renal cell carcinoma, recurrent / refractory mantle cell lymphoma (MCL) and
gastro-intestinal stroma tumors (GIST) under the conditions of routine use
Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis
Active, not recruiting
National Cancer Institute (NCI)
Phase 2
2012-03-26
This randomized phase IIA trial studies how well antiandrogen therapy works with or without
axitinib before surgery in treating patients with previously untreated prostate cancer that
is known or suspected to have spread to lymph nodes. Androgens can cause the growth of
prostate cancer cells. Antihormone therapy, such as antiandrogen therapy may lessen the
amount of androgen made by the body. Axitinib may stop the growth of tumor cells by blocking
some of the enzymes needed for cell growth. It is not yet known if antiandrogen therapy is
more effective with or without axitinib before surgery in treating patients with prostate
cancer.
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