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Last Updated: November 27, 2022

CLINICAL TRIALS PROFILE FOR INDOCIN SR


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All Clinical Trials for Indocin Sr

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002796 ↗ Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer Terminated National Cancer Institute (NCI) Phase 1/Phase 2 1997-05-01 Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interferon-gamma may interfere with the growth of tumor cells and slow the growth of the tumor. Combining more than one drug with interferon-gamma may kill more tumor cells. This phase I/II trial is studying the side effects and best dose of giving fluorouracil together with phenylbutyrate, indomethacin, and interferon-gamma and to see how well it works in treating patients with stage IV colorectal cancer
NCT00210470 ↗ A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer Completed Brooklyn ImmunoTherapeutics, LLC Phase 2 2005-07-01 This was a Phase 2a trial to investigate the safety and biological activity of the RIX-2 Regimen in patients with untreated, resectable squamous cell cancer of the head and neck (HNSCC).
NCT00210470 ↗ A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer Completed IRX Therapeutics Phase 2 2005-07-01 This was a Phase 2a trial to investigate the safety and biological activity of the RIX-2 Regimen in patients with untreated, resectable squamous cell cancer of the head and neck (HNSCC).
NCT00223691 ↗ Treatment of Orthostatic Hypotension in Autonomic Failure Completed Vanderbilt University Phase 1 2002-03-01 The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.
NCT00223691 ↗ Treatment of Orthostatic Hypotension in Autonomic Failure Completed Vanderbilt University Medical Center Phase 1 2002-03-01 The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.
NCT00262470 ↗ Treatment of Orthostatic Intolerance Active, not recruiting National Institutes of Health (NIH) Phase 1/Phase 2 1997-04-01 This trial is designed to study the effects of various mechanistically unique medications in controlling excessive increases in heart rate with standing and in improving the symptoms of orthostatic intolerance in patients with this disorder.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Indocin Sr

Condition Name

Condition Name for Indocin Sr
Intervention Trials
Obstetric Labor, Premature 2
Stage IV Prostate Cancer 2
Post-ERCP Acute Pancreatitis 2
Preterm Labor 1
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Condition MeSH

Condition MeSH for Indocin Sr
Intervention Trials
Pancreatitis 4
Obstetric Labor, Premature 3
Prostatic Neoplasms 2
Carcinoma 2
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Clinical Trial Locations for Indocin Sr

Trials by Country

Trials by Country for Indocin Sr
Location Trials
United States 44
India 6
Canada 2
Denmark 1
Singapore 1
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Trials by US State

Trials by US State for Indocin Sr
Location Trials
California 5
Pennsylvania 3
Michigan 3
Massachusetts 3
Kentucky 3
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Clinical Trial Progress for Indocin Sr

Clinical Trial Phase

Clinical Trial Phase for Indocin Sr
Clinical Trial Phase Trials
Phase 4 1
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Indocin Sr
Clinical Trial Phase Trials
Completed 12
Active, not recruiting 3
Terminated 2
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Clinical Trial Sponsors for Indocin Sr

Sponsor Name

Sponsor Name for Indocin Sr
Sponsor Trials
National Cancer Institute (NCI) 3
Brooklyn ImmunoTherapeutics, LLC 3
IRX Therapeutics 3
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Sponsor Type

Sponsor Type for Indocin Sr
Sponsor Trials
Other 37
Industry 7
NIH 4
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