Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia
Completed
National Cancer Institute (NCI)
Phase 2
1999-06-01
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the
development of cancer. Applying topical imiquimod before abnormal cervical cells are removed
may be effective in preventing cervical cancer.
PURPOSE: Randomized phase II trial to study the effectiveness of applying topical imiquimod
before abnormal cervical cells are removed in preventing cervical cancer in patients who have
recurrent or persistent cervical neoplasia.
Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia
Completed
Alliance for Clinical Trials in Oncology
Phase 2
1999-06-01
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the
development of cancer. Applying topical imiquimod before abnormal cervical cells are removed
may be effective in preventing cervical cancer.
PURPOSE: Randomized phase II trial to study the effectiveness of applying topical imiquimod
before abnormal cervical cells are removed in preventing cervical cancer in patients who have
recurrent or persistent cervical neoplasia.
Topical Imiquimod Compared With Surgery in Treating Patients With Basal Cell Skin Cancer
Completed
Queen's Medical Centre
Phase 3
2002-10-01
RATIONALE: Biological therapies such as imiquimod use different ways to stimulate the immune
system and stop cancer cells from growing. It is not yet known if topical imiquimod is more
effective than surgery in treating basal cell skin cancer.
PURPOSE: This randomized phase III trial is studying how well topical imiquimod works
compared to surgery in treating patients with basal cell skin cancer.
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