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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE


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All Clinical Trials for Ibuprofen And Diphenhydramine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00122278 ↗ Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines Completed Montefiore Medical Center Phase 3 2005-07-01 Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines. Another problem with migraines is that although many times they get better after intravenous (IV) treatment in the emergency room (ER), about 1/3 of the time migraines recur the next day. The purpose of this research project is to see if adding a medication called dexamethasone to standard ER therapy will help patients get better quicker and stay pain-free more often than if they receive placebo.
NCT00129506 ↗ Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion Completed Ibis Reproductive Health Phase 4 2005-05-01 Background: In most countries in which abortion is legal, medical abortions are induced with mifepristone and misoprostol. Since mifepristone is expensive and unavailable in many countries, it is important to find other regimens. Methotrexate, which is used with misoprostol in Canada, is also difficult to obtain in many countries. Misoprostol is inexpensive and available in almost all countries. A report from Nigeria found that 98% of 100 women aborted within 24 hours of using misoprostol given both sublingually and vaginally. Method: This will be a randomized controlled trial of the usual regimen used in Canada, methotrexate 50 mg/m2 intramuscularly (IM) followed three days later by 800 mcg vaginal misoprostol to the Nigerian regimen of 400 mcg sublingual misoprostol with 400 mcg vaginal misoprostol. The main outcome measure will be a completed abortion within the first week with secondary outcome measures including total surgery rate, time to abortion, complications, pain, side effects and patient satisfaction. Rationale: If the investigators can find an inexpensive, easily available, method of medical abortion, it will save many lives in third world countries.
NCT00129506 ↗ Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion Completed Wiebe, Ellen, M.D. Phase 4 2005-05-01 Background: In most countries in which abortion is legal, medical abortions are induced with mifepristone and misoprostol. Since mifepristone is expensive and unavailable in many countries, it is important to find other regimens. Methotrexate, which is used with misoprostol in Canada, is also difficult to obtain in many countries. Misoprostol is inexpensive and available in almost all countries. A report from Nigeria found that 98% of 100 women aborted within 24 hours of using misoprostol given both sublingually and vaginally. Method: This will be a randomized controlled trial of the usual regimen used in Canada, methotrexate 50 mg/m2 intramuscularly (IM) followed three days later by 800 mcg vaginal misoprostol to the Nigerian regimen of 400 mcg sublingual misoprostol with 400 mcg vaginal misoprostol. The main outcome measure will be a completed abortion within the first week with secondary outcome measures including total surgery rate, time to abortion, complications, pain, side effects and patient satisfaction. Rationale: If the investigators can find an inexpensive, easily available, method of medical abortion, it will save many lives in third world countries.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Ibuprofen And Diphenhydramine Hydrochloride

Condition Name

Condition Name for Ibuprofen And Diphenhydramine Hydrochloride
Intervention Trials
Healthy 2
Pain 2
Refractory B Acute Lymphoblastic Leukemia 1
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Condition MeSH

Condition MeSH for Ibuprofen And Diphenhydramine Hydrochloride
Intervention Trials
Headache 2
Migraine Disorders 2
Pain, Postoperative 1
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Clinical Trial Locations for Ibuprofen And Diphenhydramine Hydrochloride

Trials by Country

Trials by Country for Ibuprofen And Diphenhydramine Hydrochloride
Location Trials
United States 7
India 2
Hungary 1
Iran, Islamic Republic of 1
Germany 1
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Trials by US State

Trials by US State for Ibuprofen And Diphenhydramine Hydrochloride
Location Trials
Utah 1
Texas 1
Massachusetts 1
New York 1
California 1
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Clinical Trial Progress for Ibuprofen And Diphenhydramine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Ibuprofen And Diphenhydramine Hydrochloride
Clinical Trial Phase Trials
Phase 4 2
Phase 3 2
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Ibuprofen And Diphenhydramine Hydrochloride
Clinical Trial Phase Trials
Completed 7
Not yet recruiting 2
Recruiting 1
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Clinical Trial Sponsors for Ibuprofen And Diphenhydramine Hydrochloride

Sponsor Name

Sponsor Name for Ibuprofen And Diphenhydramine Hydrochloride
Sponsor Trials
Dr. Reddy's Laboratories Limited 2
National Cancer Institute (NCI) 1
Montefiore Medical Center 1
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Sponsor Type

Sponsor Type for Ibuprofen And Diphenhydramine Hydrochloride
Sponsor Trials
Other 9
Industry 6
NIH 1
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