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Generated: April 24, 2019

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CLINICAL TRIALS PROFILE FOR IBUPROFEN

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Clinical Trials for Ibuprofen

Trial ID Title Status Sponsor Phase Summary
NCT00000574 Ibuprofen in Sepsis Study Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To determine the effects of ibuprofen on mortality, development and reversal of shock, and adult respiratory distress syndrome, and on Lung Parenchymal Injury Score in adult patients with serious infection.
NCT00000574 Ibuprofen in Sepsis Study Completed Vanderbilt University Medical Center Phase 3 To determine the effects of ibuprofen on mortality, development and reversal of shock, and adult respiratory distress syndrome, and on Lung Parenchymal Injury Score in adult patients with serious infection.
NCT00000728 Phase I Trial of the Combination of Zidovudine and Recombinant Interleukin-2 in Patients With Persistent Generalized Lymphadenopathy Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 To evaluate the short-term effects of administering zidovudine ( AZT ) at the same time with increasing doses of aldesleukin ( interleukin-2; IL-2 ) in patients with persistent generalized lymphadenopathy syndrome ( PGL ). The effects to be studied include safety or toxicity, how quickly the drugs are used in the body, effects on the immune system, effects on HIV, concentrations in body fluids, and how quickly the drugs are cleared by the kidneys. The trial will establish the maximum tolerated dose ( MTD ) and will be a pilot study to determine the dose that has the greatest effect in the immune system. AZT has been shown to be effective in HIV-related disease. IL-2 has been shown to increase immune responses and correct immune problems caused by HIV in the test tube. IL-2 has also been effective in treating Kaposi's sarcoma in a number of patients. Because of the clinical activities of these two drugs and because their toxicities and mechanisms of action do not overlap, it may be beneficial to combine the two drugs with their antiviral and immune stimulatory effects.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Ibuprofen

Condition Name

Condition Name for Ibuprofen
Intervention Trials
Pain 87
Healthy 30
Patent Ductus Arteriosus 24
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Condition MeSH

Condition MeSH for Ibuprofen
Intervention Trials
Pain, Postoperative 63
Osteoarthritis 36
Ductus Arteriosus, Patent 33
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Clinical Trial Locations for Ibuprofen

Trials by Country

Trials by Country for Ibuprofen
Location Trials
United States 731
Canada 43
United Kingdom 41
Germany 26
Brazil 26
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Trials by US State

Trials by US State for Ibuprofen
Location Trials
California 54
Texas 52
Pennsylvania 42
New York 41
Utah 35
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Clinical Trial Progress for Ibuprofen

Clinical Trial Phase

Clinical Trial Phase for Ibuprofen
Clinical Trial Phase Trials
Phase 4 171
Phase 3 115
Phase 2/Phase 3 20
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Clinical Trial Status

Clinical Trial Status for Ibuprofen
Clinical Trial Phase Trials
Completed 299
Recruiting 99
Not yet recruiting 81
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Clinical Trial Sponsors for Ibuprofen

Sponsor Name

Sponsor Name for Ibuprofen
Sponsor Trials
Pfizer 42
Merck Sharp & Dohme Corp. 18
Cumberland Pharmaceuticals 17
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Sponsor Type

Sponsor Type for Ibuprofen
Sponsor Trials
Other 547
Industry 255
U.S. Fed 26
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