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Healthtrust
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Generated: December 17, 2018

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CLINICAL TRIALS PROFILE FOR IBRANCE

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Clinical Trials for Ibrance

Trial ID Title Status Sponsor Phase Summary
NCT01209598 PD0332991 (Palbociclib) in Patients With Advanced or Metastatic Liposarcoma Completed Pfizer Phase 2 The purpose of this study is to find out what effects, good and/or bad, Palbociclib (Ibrance) (formerly known as PD0332991) has on the patient and on the liposarcoma. Palbociclib is an investigational drug. An investigational drug is a medication that has not been approved for marketing by the Food and Drug Administration (FDA). Palbociclib blocks a protein called CDK4 which is part of a pathway in liposarcoma cells that is over-active. The investigators hope that blocking CDK4 will shut down this pathway in the liposarcoma cells and stop tumors from growing. Palbociclib is an oral medication.
NCT01209598 PD0332991 (Palbociclib) in Patients With Advanced or Metastatic Liposarcoma Completed Memorial Sloan Kettering Cancer Center Phase 2 The purpose of this study is to find out what effects, good and/or bad, Palbociclib (Ibrance) (formerly known as PD0332991) has on the patient and on the liposarcoma. Palbociclib is an investigational drug. An investigational drug is a medication that has not been approved for marketing by the Food and Drug Administration (FDA). Palbociclib blocks a protein called CDK4 which is part of a pathway in liposarcoma cells that is over-active. The investigators hope that blocking CDK4 will shut down this pathway in the liposarcoma cells and stop tumors from growing. Palbociclib is an oral medication.
NCT01864746 A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery Recruiting AGO Study Group Phase 3 The PENELOPEB study is designed to demonstrate that in the background of standard anti-hormonal therapy palbociclib provides superior invasive disease-free survival (iDFS) compared to placebo in pre- and postmenopausal women with HR-positive/HER2-normal early breast cancer at high risk of relapse after showing less than pathological complete response to neoadjuvant taxane- containing chemotherapy. Considering the high risk of recurrence in patients after neoadjuvant chemotherapy and a high CPS-EG score, palbociclib appears to be an attractive option with a favourable safety profile for these patients.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Ibrance

Condition Name

Condition Name for Ibrance
Intervention Trials
Breast Cancer 10
Metastatic Breast Cancer 8
HER2/Neu Negative 4
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Condition MeSH

Condition MeSH for Ibrance
Intervention Trials
Breast Neoplasms 35
Neoplasms 8
Carcinoma 7
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Clinical Trial Locations for Ibrance

Trials by Country

Trials by Country for Ibrance
Location Trials
United States 258
Spain 6
Australia 6
Sweden 3
Brazil 3
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Trials by US State

Trials by US State for Ibrance
Location Trials
California 11
Missouri 10
Maryland 9
Illinois 9
North Carolina 9
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Clinical Trial Progress for Ibrance

Clinical Trial Phase

Clinical Trial Phase for Ibrance
Clinical Trial Phase Trials
Phase 4 1
Phase 3 3
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for Ibrance
Clinical Trial Phase Trials
Recruiting 40
Not yet recruiting 19
Completed 1
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Clinical Trial Sponsors for Ibrance

Sponsor Name

Sponsor Name for Ibrance
Sponsor Trials
Pfizer 33
National Cancer Institute (NCI) 10
Dana-Farber Cancer Institute 5
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Sponsor Type

Sponsor Type for Ibrance
Sponsor Trials
Other 78
Industry 50
NIH 10
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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Fuji
AstraZeneca
Express Scripts
Dow
McKesson
Colorcon
Queensland Health
Covington

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