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Last Updated: October 20, 2019

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CLINICAL TRIALS PROFILE FOR HYDROXYUREA

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Clinical Trials for Hydroxyurea

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000586 Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1992-01-01 To assess the efficacy and safety of orally administered hydroxyurea in the treatment of painful crises in patients with sickle cell anemia.
NCT00000602 Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 2 1994-04-01 To determine whether hydroxyurea prevents the onset of chronic end organ damage in young children with sickle cell anemia.
NCT00000623 Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN) Completed National Heart, Lung, and Blood Institute (NHLBI) N/A 2000-07-01 The purpose of the TCRN is to accelerate research in the management of thalassemia, standardize existing treatments, and evaluate new ones in a network of clinical centers in North America. The emphasis will be on clinical trials that help identify optimal therapy. Therapeutic trials may involve investigational drugs, drugs already approved but not currently used, and drugs currently used.
NCT00000623 Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN) Completed Thalassemia Clinical Research Network N/A 2000-07-01 The purpose of the TCRN is to accelerate research in the management of thalassemia, standardize existing treatments, and evaluate new ones in a network of clinical centers in North America. The emphasis will be on clinical trials that help identify optimal therapy. Therapeutic trials may involve investigational drugs, drugs already approved but not currently used, and drugs currently used.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Hydroxyurea

Condition Name

Condition Name for Hydroxyurea
Intervention Trials
Sickle Cell Disease 46
Sickle Cell Anemia 30
HIV Infections 17
Polycythemia Vera 17
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Condition MeSH

Condition MeSH for Hydroxyurea
Intervention Trials
Anemia, Sickle Cell 87
Leukemia 29
Leukemia, Myeloid 29
Anemia 25
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Clinical Trial Locations for Hydroxyurea

Trials by Country

Trials by Country for Hydroxyurea
Location Trials
United States 661
Italy 61
Germany 37
France 33
Spain 26
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Trials by US State

Trials by US State for Hydroxyurea
Location Trials
Illinois 43
New York 39
Texas 38
North Carolina 37
Maryland 36
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Clinical Trial Progress for Hydroxyurea

Clinical Trial Phase

Clinical Trial Phase for Hydroxyurea
Clinical Trial Phase Trials
Phase 4 7
Phase 3 45
Phase 2/Phase 3 6
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Clinical Trial Status

Clinical Trial Status for Hydroxyurea
Clinical Trial Phase Trials
Completed 93
Recruiting 55
Terminated 21
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Clinical Trial Sponsors for Hydroxyurea

Sponsor Name

Sponsor Name for Hydroxyurea
Sponsor Trials
National Cancer Institute (NCI) 24
National Heart, Lung, and Blood Institute (NHLBI) 22
Novartis Pharmaceuticals 17
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Sponsor Type

Sponsor Type for Hydroxyurea
Sponsor Trials
Other 259
Industry 92
NIH 67
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