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Last Updated: February 7, 2023

CLINICAL TRIALS PROFILE FOR HYDELTRA-TBA


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All Clinical Trials for Hydeltra-tba

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00900445 ↗ Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk Acute Lymphoblastic Leukemia Withdrawn National Cancer Institute (NCI) 2008-03-24 This clinical trial is studying body mass index in younger patients receiving prednisone/prednisolone, vincristine, daunorubicin, and pegaspargase for high-risk acute lymphoblastic leukemia. Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about the affect of body mass index on the way anticancer drugs work in the body. It may also help doctors predict how patients will respond to treatment
NCT00900445 ↗ Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk Acute Lymphoblastic Leukemia Withdrawn Children's Oncology Group 2008-03-24 This clinical trial is studying body mass index in younger patients receiving prednisone/prednisolone, vincristine, daunorubicin, and pegaspargase for high-risk acute lymphoblastic leukemia. Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about the affect of body mass index on the way anticancer drugs work in the body. It may also help doctors predict how patients will respond to treatment
NCT02828358 ↗ Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement Active, not recruiting National Cancer Institute (NCI) Phase 2 2017-03-27 This pilot phase II trial studies the side effects of azacitidine and combination chemotherapy in infants with acute lymphoblastic leukemia and KMT2A gene rearrangement. Drugs used in chemotherapy, such as methotrexate, prednisolone, daunorubicin hydrochloride, cytarabine, dexamethasone, vincristine sulfate, pegaspargase, hydrocortisone sodium succinate, azacitidine, cyclophosphamide, mercaptopurine, leucovorin calcium, and thioguanine work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving more than one drug may kill more cancer cells.
NCT03007147 ↗ Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Recruiting EsPhALL network I-BFM Study Group Phase 3 2017-07-28 This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving imatinib mesylate and combination chemotherapy may work better in treating patients with Philadelphia chromosome positive acute lymphoblastic leukemia.
NCT03007147 ↗ Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Recruiting National Cancer Institute (NCI) Phase 3 2017-07-28 This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving imatinib mesylate and combination chemotherapy may work better in treating patients with Philadelphia chromosome positive acute lymphoblastic leukemia.
NCT03007147 ↗ Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Recruiting Children's Oncology Group Phase 3 2017-07-28 This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving imatinib mesylate and combination chemotherapy may work better in treating patients with Philadelphia chromosome positive acute lymphoblastic leukemia.
NCT03914625 ↗ A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia Recruiting National Cancer Institute (NCI) Phase 3 2019-06-28 This phase III trial studies how well blinatumomab works in combination with chemotherapy in treating patients with newly diagnosed, standard risk B-lymphoblastic leukemia or B-lymphoblastic lymphoma with or without Down syndrome. Monoclonal antibodies, such as blinatumomab, may induce changes in the body's immune system and may interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, such as vincristine, dexamethasone, prednisone, prednisolone, pegaspargase, methotrexate, cytarabine, mercaptopurine, doxorubicin, cyclophosphamide, and thioguanine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Leucovorin decreases the toxic effects of methotrexate. Giving monoclonal antibody therapy with chemotherapy may kill more cancer cells. Giving blinatumomab and combination chemotherapy may work better than combination chemotherapy alone in treating patients with B-ALL. This trial also assigns patients into different chemotherapy treatment regimens based on risk (the chance of cancer returning after treatment). Treating patients with chemotherapy based on risk may help doctors decide which patients can best benefit from which chemotherapy treatment regimens.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Hydeltra-tba

Condition Name

Condition Name for Hydeltra-tba
Intervention Trials
B Acute Lymphoblastic Leukemia 4
Mixed Phenotype Acute Leukemia 3
Acute Lymphoblastic Leukemia 2
B Lymphoblastic Lymphoma 2
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Condition MeSH

Condition MeSH for Hydeltra-tba
Intervention Trials
Leukemia, Lymphoid 6
Leukemia 6
Precursor Cell Lymphoblastic Leukemia-Lymphoma 6
Lymphoma 3
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Clinical Trial Locations for Hydeltra-tba

Trials by Country

Trials by Country for Hydeltra-tba
Location Trials
United States 233
Canada 30
Australia 15
New Zealand 6
Puerto Rico 4
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Trials by US State

Trials by US State for Hydeltra-tba
Location Trials
Oklahoma 6
California 6
South Carolina 6
Tennessee 6
Texas 6
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Clinical Trial Progress for Hydeltra-tba

Clinical Trial Phase

Clinical Trial Phase for Hydeltra-tba
Clinical Trial Phase Trials
Phase 3 5
Phase 2 1
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Hydeltra-tba
Clinical Trial Phase Trials
Recruiting 4
Not yet recruiting 2
Withdrawn 1
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Clinical Trial Sponsors for Hydeltra-tba

Sponsor Name

Sponsor Name for Hydeltra-tba
Sponsor Trials
National Cancer Institute (NCI) 8
Children's Oncology Group 4
EsPhALL network I-BFM Study Group 1
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Sponsor Type

Sponsor Type for Hydeltra-tba
Sponsor Trials
NIH 8
Other 5
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Serving leading biopharmaceutical companies globally:

Harvard Business School
McKinsey
Merck
AstraZeneca
Medtronic
Dow

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