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Last Updated: February 29, 2024

CLINICAL TRIALS PROFILE FOR HYCAMTIN


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All Clinical Trials for Hycamtin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002913 ↗ Paclitaxel, Cisplatin, and Topotecan With or Without Filgrastim in Treating Patients With Newly Diagnosed Stage III or Stage IV Epithelial Ovarian Cancer Completed National Cancer Institute (NCI) Phase 1 1996-12-01 Phase I trial to study the effectiveness of paclitaxel, cisplatin, and topotecan with or without filgrastim in treating patients who have newly diagnosed stage III or stage IV epithelial ovarian cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy
NCT00003415 ↗ Amifostine Plus Topotecan in Treating Patients With Myelodysplastic Syndrome Completed University of Arizona Phase 1/Phase 2 1998-09-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase I/II trial to study the effectiveness of amifostine plus topotecan in treating patients with myelodysplastic syndrome.
NCT00003733 ↗ Sequential Chemotherapy in Treating Patients With Residual Disease Following Surgery for Stage IIB, Stage III, or Stage IV Ovarian Cancer Unknown status SmithKline Beecham Phase 2 1997-12-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs in different ways may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of sequential chemotherapy in treating patients with residual disease following surgery for stage IIB, stage III, or stage IV ovarian cancer.
NCT00003958 ↗ Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma Completed National Cancer Institute (NCI) Phase 3 2002-09-01 This randomized phase III trial is comparing two different combination chemotherapy regimens to see how well each works in treating patients with previously untreated rhabdomyosarcoma or sarcoma. Drugs used in chemotherapy, such as dactinomycin, cyclophosphamide, vincristine, and topotecan, use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective in treating rhabdomyosarcoma.
NCT00003958 ↗ Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma Completed Children's Oncology Group Phase 3 2002-09-01 This randomized phase III trial is comparing two different combination chemotherapy regimens to see how well each works in treating patients with previously untreated rhabdomyosarcoma or sarcoma. Drugs used in chemotherapy, such as dactinomycin, cyclophosphamide, vincristine, and topotecan, use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective in treating rhabdomyosarcoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Hycamtin

Condition Name

Condition Name for Hycamtin
Intervention Trials
Ovarian Cancer 13
Neuroblastoma 11
Solid Tumors 6
Unspecified Adult Solid Tumor, Protocol Specific 5
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Condition MeSH

Condition MeSH for Hycamtin
Intervention Trials
Small Cell Lung Carcinoma 29
Lung Neoplasms 27
Ovarian Neoplasms 27
Carcinoma, Ovarian Epithelial 23
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Clinical Trial Locations for Hycamtin

Trials by Country

Trials by Country for Hycamtin
Location Trials
United States 935
Canada 78
Australia 22
Germany 16
United Kingdom 13
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Trials by US State

Trials by US State for Hycamtin
Location Trials
California 41
Texas 34
Ohio 34
Florida 31
New York 31
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Clinical Trial Progress for Hycamtin

Clinical Trial Phase

Clinical Trial Phase for Hycamtin
Clinical Trial Phase Trials
Phase 4 1
Phase 3 18
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Hycamtin
Clinical Trial Phase Trials
Completed 60
Active, not recruiting 14
Recruiting 13
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Clinical Trial Sponsors for Hycamtin

Sponsor Name

Sponsor Name for Hycamtin
Sponsor Trials
National Cancer Institute (NCI) 48
GlaxoSmithKline 21
Children's Oncology Group 11
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Sponsor Type

Sponsor Type for Hycamtin
Sponsor Trials
Other 96
Industry 54
NIH 49
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