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CLINICAL TRIALS PROFILE FOR HALOBETASOL PROPIONATE

Clinical Trials for Halobetasol Propionate

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00715975	Effectiveness and Safety of Topical Halobetasol Propionate in the Treatment of Patients With Psoriasis	Completed	Azidus Brasil	Phase 2/Phase 3	2008-07-01	The Psoriasis and a chronic dermatosis characterized by abnormal proliferation of cells epithelial, vessel dilation and inflammation locally, which presents erythematous-scaly lesions in various areas of the body, preferably in the scalp, region and religious joints as elbows and knees. It occurs equally in both sexes and can appear at any age, and the mean age for the onset of the disease and around 27.3 years. The halobetasol propionate and an ultra-potent corticoid. Its chemical structure and similar to the Clobetasol corticoid this, until then classified as the most potent corticoid used worldwide in clinical practice. However, the molecular structure of Halobetasol gives it increased its activity antiinflammatory and anti-proliferative. The objective of this study is evaluating the efficacy and tolerability of the drug Halobetasol propionate cream formulation as a treatment in patients with plaque psoriasis mild to moderate, compared to the substance of similar power, Clobetasol propionate - Psorex - Cream.
NCT00802958	Randomized Study to Compare the Bioavailability of Two Halobetasol Propionate 0.05% Topical Ointments	Completed	Perrigo Company	N/A	2003-07-01	The purpose of this study was to compare the relative vasoconstrictive effects of test and reference Halobetasol Propionate 0.05% Ointment in healthy, female subjects.
NCT00803166	Randomized Study to Compare the Bioavailability of Three Halobetasol Propionate 0.05% Topical Creams	Completed	Perrigo Company	N/A	2004-01-01	The purpose of this study was to compare the relative vasoconstrictive effects of two test and one reference Halobetasol Propionate 0.05% Cream in healthy, female subjects.
NCT00865267	The Dose-response Study of Topically Delivered Halobetasol Propionate Ointment in Normal Skin in Healthy Adult Subjects	Completed	Actavis Inc.	Phase 1	2003-12-01	The purpose of this study is to determine the duration of application of halobetasol propionate 0.05% ointment to be used in a definitive study of bioequivalence of to formulations of this ointment. Part A: To validate vasoconstrictor assay precision. Part B: To evaluate the dose response vasoconstriction profile of Ultravate® 0.05% ointment at different dose durations over a short period of time (0.17 - 4 hrs).
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary