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Generated: December 13, 2018

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CLINICAL TRIALS PROFILE FOR GLUCAGON HYDROCHLORIDE

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Clinical Trials for Glucagon Hydrochloride

Trial ID Title Status Sponsor Phase Summary
NCT00005889 Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion Unknown status Baylor College of Medicine N/A RATIONALE: Very low birth weight infants have problems maintaining normal blood sugar levels. Gluconeogenesis is the production of sugar from amino acids and fats. The best combination of amino acids, fat, and sugar to help very low birth weigh infants maintain normal blood sugar levels is not yet known. PURPOSE: Clinical trial to study how very low birth weight infants break down amino acids, fat, and sugar given by intravenous infusion, and the effect of different combinations of nutrients on the infants' ability to maintain normal blood sugar levels.
NCT00005889 Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion Unknown status National Center for Research Resources (NCRR) N/A RATIONALE: Very low birth weight infants have problems maintaining normal blood sugar levels. Gluconeogenesis is the production of sugar from amino acids and fats. The best combination of amino acids, fat, and sugar to help very low birth weigh infants maintain normal blood sugar levels is not yet known. PURPOSE: Clinical trial to study how very low birth weight infants break down amino acids, fat, and sugar given by intravenous infusion, and the effect of different combinations of nutrients on the infants' ability to maintain normal blood sugar levels.
NCT00013910 NNC 90-1170 Mechanism of Action: A Double-Blind, Randomized, Single-Center, Placebo-Controlled, Crossover Study to Examine Beta-Cell Responsiveness to Graded Glucose Infusion in Subjects With Type 2 Diabetes Completed National Center for Research Resources (NCRR) Phase 1 The purpose of this research study is to investigate the mechanism of action of a new investigational medication (drug), NNC 90-1170, which is being developed for the treatment of type 2 diabetes (adult onset type of diabetes. NNC 90-1170 is a modified form of a hormone, Glucagon-Like Peptide 1 (or GLP-1), which is important for controlling insulin levels. Insulin, another hormone, is also important for controlling blood glucose levels, which are higher than normal in people who have type 2 diabetes. This study will measure the effect of NNC 90-1170, active investigational drug, to cause insulin to be released from the pancreas in response to increasing blood glucose concentrations. These results will be compared to that of a group of healthy volunteers of similar age and body weight who do not have diabetes. Also, various other hormones and substances that are known to control blood sugar will be measured in blood samples that will be drawn. One dose of NNC 90-1170 will be given to subjects with type 2 diabetes only in this study, and the effects of this dose will be compared to a placebo (inactive substance that looks like the active drug). This is a crossover study, which means that subjects will be treated both with NNC 90-1170 and with placebo. The order in which subjects will receive the treatments will be determined by chance (randomly). The study will be conducted as a so-called "double-blind" study, meaning that neither subjects nor study doctors will know the order in which subjects will be given each treatment until the study is over. The study will include approximately 15 healthy volunteers and 15 volunteers with type 2 diabetes, and it will be conducted at 1 clinic (the University of Michigan Health System) in the United States.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Glucagon Hydrochloride

Condition Name

Condition Name for Glucagon Hydrochloride
Intervention Trials
Type 2 Diabetes 72
Type 2 Diabetes Mellitus 66
Diabetes Mellitus, Type 2 45
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Condition MeSH

Condition MeSH for Glucagon Hydrochloride
Intervention Trials
Diabetes Mellitus 282
Diabetes Mellitus, Type 2 203
Diabetes Mellitus, Type 1 97
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Clinical Trial Locations for Glucagon Hydrochloride

Trials by Country

Trials by Country for Glucagon Hydrochloride
Location Trials
United States 606
Denmark 72
Canada 48
Germany 39
United Kingdom 37
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Trials by US State

Trials by US State for Glucagon Hydrochloride
Location Trials
Texas 49
California 40
New York 33
Pennsylvania 27
Massachusetts 26
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Clinical Trial Progress for Glucagon Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Glucagon Hydrochloride
Clinical Trial Phase Trials
Phase 4 158
Phase 3 82
Phase 2/Phase 3 16
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Clinical Trial Status

Clinical Trial Status for Glucagon Hydrochloride
Clinical Trial Phase Trials
Completed 283
Recruiting 146
Not yet recruiting 60
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Clinical Trial Sponsors for Glucagon Hydrochloride

Sponsor Name

Sponsor Name for Glucagon Hydrochloride
Sponsor Trials
Novo Nordisk A/S 30
University Hospital, Gentofte, Copenhagen 27
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 26
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Sponsor Type

Sponsor Type for Glucagon Hydrochloride
Sponsor Trials
Other 666
Industry 257
NIH 48
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