Efficacy and Safety of Fosrenol in Treating Elevated Serum Phosphate Levels in Adults With End Stage Renal Disease
Completed
Shire
Phase 4
2005-01-10
The purpose of this study is to test how well lanthanum carbonate reduces the pre-dialysis
level of serum phosphorus in subjects undergoing dialysis due to end stage renal disease and
to determine the patient and physician's satisfaction.
Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease
Completed
Shire
Phase 2
2006-01-11
Chronic kidney disease (CKD) can result in a loss of ability to filter and excrete phosphate.
The body's attempt to adjust to an increased level of phosphate in the blood can result in
elevated levels of hormones and minerals resulting in serious clinical consequences. This
study is being conducted to evaluate the safety and efficacy of lanthanum carbonate in
lowering high levels of phosphorus in the blood in subjects with CKD Stages 3 and 4 compared
to placebo.
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