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Generated: December 14, 2018

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CLINICAL TRIALS PROFILE FOR FOLOTYN

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Clinical Trials for Folotyn

Trial ID Title Status Sponsor Phase Summary
NCT00481871 Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies Completed Spectrum Pharmaceuticals, Inc Phase 1/Phase 2 This study is for patients with lymphoproliferative malignancies that have progressed after receiving a previous treatment (relapsed) or are no longer responding to treatment (refractory). To be in this study, patients must have certain types of Hodgkin's lymphoma (HL), peripheral T-cell lymphoma (PTCL), or B-cell lymphoma, including Waldenstrom's macroglobulinemia. This study is being done to find doses of the combination of pralatrexate and gemcitabine with vitamin B12 and folic acid that can be safely given to patients with these types of lymphoma and explore the effectiveness of the treatment.
NCT00606502 Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment Completed Spectrum Pharmaceuticals, Inc Phase 2 The purpose of this clinical study is to determine the effectiveness (ability to provide beneficial treatment of the disease) and safety of pralatrexate compared to erlotinib when given to non-small cell lung cancer (NSCLC) patients who are current or former cigarette smokers and who have received at least 1 prior treatment with a platinum drug (cisplatin or carboplatin)
NCT01129206 Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy Completed National Comprehensive Cancer Network Phase 2 RATIONALE: Pralatrexate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving pralatrexate together with docetaxel may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving pralatrexate together with docetaxel works in treating patients with stage IV esophageal or gastroesophageal cancer who have failed platinum-based therapy.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Folotyn

Condition Name

Condition Name for Folotyn
Intervention Trials
Peripheral T-cell Lymphoma 3
Non-small Cell Lung Cancer 2
Lymphoma, T-Cell 1
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Condition MeSH

Condition MeSH for Folotyn
Intervention Trials
Lymphoma 13
Lymphoma, T-Cell 10
Lymphoma, T-Cell, Peripheral 8
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Clinical Trial Locations for Folotyn

Trials by Country

Trials by Country for Folotyn
Location Trials
United States 60
India 7
United Kingdom 7
Hungary 5
Australia 4
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Trials by US State

Trials by US State for Folotyn
Location Trials
New York 9
California 7
Washington 4
Texas 4
New Jersey 4
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Clinical Trial Progress for Folotyn

Clinical Trial Phase

Clinical Trial Phase for Folotyn
Clinical Trial Phase Trials
Phase 4 1
Phase 3 2
Phase 2 6
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Clinical Trial Status

Clinical Trial Status for Folotyn
Clinical Trial Phase Trials
Completed 6
Recruiting 4
Not yet recruiting 3
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Clinical Trial Sponsors for Folotyn

Sponsor Name

Sponsor Name for Folotyn
Sponsor Trials
Spectrum Pharmaceuticals, Inc 10
National Cancer Institute (NCI) 4
Columbia University 2
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Sponsor Type

Sponsor Type for Folotyn
Sponsor Trials
Other 12
Industry 12
NIH 4
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