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Last Updated: July 3, 2022

CLINICAL TRIALS PROFILE FOR FLORTAUCIPIR F-18


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All Clinical Trials for Flortaucipir F-18

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01992380 ↗ A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired Subjects Completed Avid Radiopharmaceuticals Phase 1 2013-11-13 This study will test if two flortaucipir PET scans up to 4 weeks apart in healthy volunteers, MCI and AD subjects provide the same results.
NCT02016560 ↗ Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI, and AD Subjects Completed Avid Radiopharmaceuticals Phase 2/Phase 3 2013-12-01 A Phase 2/3 cross-sectional and longitudinal observational study evaluating imaging characteristics of flortaucipir in control subjects and patients with clinically defined MCI and AD dementia (AD).
NCT02051764 ↗ Imaging Characteristics of a Follow-up 18F-AV-1451 Scan Terminated Avid Radiopharmaceuticals Phase 2 2014-05-01 This study will evaluate the imaging characteristics of flortaucipir in subjects with a previous flortaucipir scan in order to assess the rate of change of tau deposition over time.
NCT02079766 ↗ 18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy Completed Avid Radiopharmaceuticals Phase 2 2014-06-01 This study will explore the use of flortaucipir as a biomarker for chronic traumatic encephalopathy (CTE) and examine the relationship between clinical presentation and tau deposition.
NCT02167594 ↗ Tau Imaging in Subjects With Progressive Supranuclear Palsy, Corticobasal Degeneration and Healthy Volunteers Completed Avid Radiopharmaceuticals Phase 1 2014-08-12 This study will evaluate flortaucipir for brain imaging of tau in subjects with progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and healthy volunteers.
NCT02278354 ↗ Tau Imaging in Professional Fighters Completed The Cleveland Clinic Phase 1 2015-02-18 Subjects enrolled in the Professional Fighters Brain Health Study (PFBHS) will receive flortaucipir to explore its use as a biomarker for brain injury related to repetitive head trauma and to examine the relationship between clinical presentation and tau deposition.
NCT02278354 ↗ Tau Imaging in Professional Fighters Completed Avid Radiopharmaceuticals Phase 1 2015-02-18 Subjects enrolled in the Professional Fighters Brain Health Study (PFBHS) will receive flortaucipir to explore its use as a biomarker for brain injury related to repetitive head trauma and to examine the relationship between clinical presentation and tau deposition.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Flortaucipir F-18

Condition Name

Condition Name for Flortaucipir F-18
Intervention Trials
Alzheimer's Disease 9
Alzheimer Disease 8
Cognitive Decline 2
Mild Cognitive Impairment 1
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Condition MeSH

Condition MeSH for Flortaucipir F-18
Intervention Trials
Alzheimer Disease 17
Dementia 3
Cognitive Dysfunction 3
Brain Injuries, Traumatic 2
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Clinical Trial Locations for Flortaucipir F-18

Trials by Country

Trials by Country for Flortaucipir F-18
Location Trials
United States 76
Australia 3
Canada 2
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Trials by US State

Trials by US State for Flortaucipir F-18
Location Trials
California 11
Pennsylvania 8
Massachusetts 6
Texas 5
Rhode Island 5
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Clinical Trial Progress for Flortaucipir F-18

Clinical Trial Phase

Clinical Trial Phase for Flortaucipir F-18
Clinical Trial Phase Trials
Phase 3 3
Phase 2/Phase 3 1
Phase 2 8
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Clinical Trial Status

Clinical Trial Status for Flortaucipir F-18
Clinical Trial Phase Trials
Completed 16
Not yet recruiting 2
Terminated 2
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Clinical Trial Sponsors for Flortaucipir F-18

Sponsor Name

Sponsor Name for Flortaucipir F-18
Sponsor Trials
Avid Radiopharmaceuticals 18
National Institute on Aging (NIA) 1
Tharick Pascoal 1
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Sponsor Type

Sponsor Type for Flortaucipir F-18
Sponsor Trials
Industry 19
Other 4
NIH 1
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