Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI, and AD Subjects
Completed
Avid Radiopharmaceuticals
Phase 2/Phase 3
2013-12-01
A Phase 2/3 cross-sectional and longitudinal observational study evaluating imaging
characteristics of flortaucipir in control subjects and patients with clinically defined MCI
and AD dementia (AD).
Imaging Characteristics of a Follow-up 18F-AV-1451 Scan
Terminated
Avid Radiopharmaceuticals
Phase 2
2014-05-01
This study will evaluate the imaging characteristics of flortaucipir in subjects with a
previous flortaucipir scan in order to assess the rate of change of tau deposition over time.
18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy
Completed
Avid Radiopharmaceuticals
Phase 2
2014-06-01
This study will explore the use of flortaucipir as a biomarker for chronic traumatic
encephalopathy (CTE) and examine the relationship between clinical presentation and tau
deposition.
Tau Imaging in Subjects With Progressive Supranuclear Palsy, Corticobasal Degeneration and Healthy Volunteers
Completed
Avid Radiopharmaceuticals
Phase 1
2014-08-12
This study will evaluate flortaucipir for brain imaging of tau in subjects with progressive
supranuclear palsy (PSP), corticobasal degeneration (CBD) and healthy volunteers.
Subjects enrolled in the Professional Fighters Brain Health Study (PFBHS) will receive
flortaucipir to explore its use as a biomarker for brain injury related to repetitive head
trauma and to examine the relationship between clinical presentation and tau deposition.
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