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Generated: December 18, 2018

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CLINICAL TRIALS PROFILE FOR ERYTHROMYCIN

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Clinical Trials for Erythromycin

Trial ID Title Status Sponsor Phase Summary
NCT00000120 Clinical Trial of Eye Prophylaxis in the Newborn Completed National Eye Institute (NEI) Phase 3 To compare the effectiveness of silver nitrate drops, erythromycin ointment, or no medication in preventing neonatal conjunctivitis caused by Chlamydia trachomatis and other eye infections. To compare side effects of the two prophylactic agents.
NCT00002194 An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4. Completed Boehringer Ingelheim Phase 1 To evaluate the potential pharmacokinetic interaction between nevirapine and clarithromycin, and to determine the effects of nevirapine on cytochrome P450 3A4 (CYP3A4) activity in vivo.
NCT00004564 The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3A Unknown status National Center for Research Resources (NCRR) N/A The objective of this study is to determine if the action of the drug called clopidogrel, that you will start taking, will be decreased by another drug called atorvastatin, that you will also start taking. Clopidogrel is an oral antiplatelet agent that has been shown to prevent strokes and heart attacks. Atorvastatin is a cholesterol lowering agent. Twenty adults 18-75 years of age requiring cholesterol-lowering agent and antiplatelet agent therapy will be recruited for this study during their cardiology clinic visitation. In one group, antiplatelet agent (clopidogrel) regimen will be administered first, then followed by cholesterol-lowering medication (atorvastatin). In the second group, atorvastatin will be administered first, followed by clopidogrel. A new test called the erythromycin breath test will be administered to you three times during the study to measure how your liver will metabolize these drugs. Blood samples will also be obtained to assess platelet function. The criteria for exclusion are patient refusal or inability to give written consent, patients with allergic reaction to erythromycin, patients with known bleeding problems, liver disease, significant lung disease kidney disease and pregnancy. Patients with psychiatric impairment and documented history of substance abuse will also be excluded from the study.
NCT00021671 Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission Completed National Institute of Mental Health (NIMH) Phase 3 The purpose of this study is to see if antibiotic drugs given to treat an infection of the uterus during pregnancy can reduce the chances of HIV being passed from an HIV-positive mother to her baby. A link between bacterial disease of the vagina, premature birth, infection of the uterus during pregnancy, and the passing of HIV from a mother to her baby has been found. Early treatment of these problems may reduce the risk of passing HIV from an HIV-positive mother to her baby. [Note: As of 02/21/03, enrollment into this study was halted because preliminary data showed that the study antibiotics were not effective in preventing mother-to-child HIV transmission.]
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Erythromycin

Condition Name

Condition Name for Erythromycin
Intervention Trials
Healthy 7
Cholera 4
Pneumonia 2
Solid Tumors 2
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Condition MeSH

Condition MeSH for Erythromycin
Intervention Trials
Cholera 4
Colorectal Neoplasms 4
Rupture 4
Hemorrhage 4
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Clinical Trial Locations for Erythromycin

Trials by Country

Trials by Country for Erythromycin
Location Trials
United States 48
Brazil 14
Bangladesh 5
Belgium 5
United Kingdom 5
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Trials by US State

Trials by US State for Erythromycin
Location Trials
Michigan 4
Kentucky 4
Pennsylvania 3
Minnesota 3
Massachusetts 3
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Clinical Trial Progress for Erythromycin

Clinical Trial Phase

Clinical Trial Phase for Erythromycin
Clinical Trial Phase Trials
Phase 4 21
Phase 3 18
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Erythromycin
Clinical Trial Phase Trials
Completed 61
Terminated 9
Unknown status 9
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Clinical Trial Sponsors for Erythromycin

Sponsor Name

Sponsor Name for Erythromycin
Sponsor Trials
International Centre for Diarrhoeal Disease Research, Bangladesh 5
Pfizer 4
Bayer 3
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Sponsor Type

Sponsor Type for Erythromycin
Sponsor Trials
Other 112
Industry 37
NIH 9
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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Johnson and Johnson
Healthtrust
Julphar
Cipla
Argus Health
Mallinckrodt
Deloitte
Moodys

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