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Last Updated: February 3, 2023

CLINICAL TRIALS PROFILE FOR EPHEDRINE HYDROCHLORIDE


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All Clinical Trials for Ephedrine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00232817 ↗ Anesthesia and Postoperative Pain Completed Columbia University Phase 4 2003-07-01 The purpose of this study is to compare post-operative pain after anesthesia with either isoflurane or propofol. Each group will be further randomized to recieve intranasal nicotine or placebo inorder to detect potetial pronociceptive action of isoflurane. The study is a randomized, prospective, double-blinded controlled trial. Eighty adult women undergoing uterine surgery will be recruited for this study. Enrollment in this study is limited to women, because our animal studies suggest that females have a greater hyperalgesic response to volatile anesthetics than do males. The patient will be given one of two standard anesthetics for their surgery: isoflurane or propofol. We are interested in these two anesthetics because we seek to see if there exists a difference in their effects on a patient's perception of pain, as has been shown to be the case in animal studies but has not yet been studied in humans. The primary outcome variable will be postoperative pain, as measured by a numerical analog pain score (VAS) at 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 120, and 1440 minutes postoperatively. Secondary outcome measures will include morphine utilization via PCA and hemodynamics variables including heart rate, systolic BP, and diastolic BP, all of which will be measured at the same time points as the VAS score.
NCT00267332 ↗ Modafinil in Opioid Induced Sedation Terminated Sidney Kimmel Comprehensive Cancer Center Phase 3 2006-01-01 - The primary objective of this study is to evaluate the efficacy of modafinil in the treatment of opioid induced sedation as measured by the Epworth Sleepiness Scale (ESS). - The secondary objective is to estimate the frequency and severity of toxicity associated with Modafinil (400mg) in patients with opioid induced sedation.
NCT00267332 ↗ Modafinil in Opioid Induced Sedation Terminated Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 3 2006-01-01 - The primary objective of this study is to evaluate the efficacy of modafinil in the treatment of opioid induced sedation as measured by the Epworth Sleepiness Scale (ESS). - The secondary objective is to estimate the frequency and severity of toxicity associated with Modafinil (400mg) in patients with opioid induced sedation.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Ephedrine Hydrochloride

Condition Name

Condition Name for Ephedrine Hydrochloride
Intervention Trials
Hypotension 23
Anesthesia 17
Spinal Anesthesia 10
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Condition MeSH

Condition MeSH for Ephedrine Hydrochloride
Intervention Trials
Hypotension 64
Pain, Postoperative 27
Pre-Eclampsia 11
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Clinical Trial Locations for Ephedrine Hydrochloride

Trials by Country

Trials by Country for Ephedrine Hydrochloride
Location Trials
United States 105
Egypt 54
Canada 23
Turkey 20
China 10
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Trials by US State

Trials by US State for Ephedrine Hydrochloride
Location Trials
New York 9
Illinois 7
California 6
Florida 5
Texas 5
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Clinical Trial Progress for Ephedrine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Ephedrine Hydrochloride
Clinical Trial Phase Trials
Phase 4 91
Phase 3 19
Phase 2/Phase 3 11
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Clinical Trial Status

Clinical Trial Status for Ephedrine Hydrochloride
Clinical Trial Phase Trials
Completed 141
Recruiting 38
Not yet recruiting 28
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Clinical Trial Sponsors for Ephedrine Hydrochloride

Sponsor Name

Sponsor Name for Ephedrine Hydrochloride
Sponsor Trials
Ain Shams University 13
Mansoura University 12
Cairo University 9
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Sponsor Type

Sponsor Type for Ephedrine Hydrochloride
Sponsor Trials
Other 261
Industry 13
U.S. Fed 1
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