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Generated: December 18, 2018

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CLINICAL TRIALS PROFILE FOR DOFETILIDE

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Clinical Trials for Dofetilide

Trial ID Title Status Sponsor Phase Summary
NCT00392106 High Intensity Focused Ultrasound (HIFU) Ablation System Study Suspended ProRhythm, Inc. Phase 3 The purpose of this study is to determine if the HIFU Pulmonary Vein Ablation System is effective in the treatment of paroxysmal Atrial Fibrillation compared to the control of best medical therapy with FDA approved antiarrhythmic drugs.
NCT00657514 Ranolazine Versus Placebo Effects on Exercise Tolerance in Patients With Heart Disease and Peripheral Arterial Disease Withdrawn Colorado Prevention Center Phase 4 After 6 weeks of maximal Ranolazine therapy, tissue hemoglobin desaturation kinetics will change compared to placebo in patients with chronic angina and peripheral arterial disease.
NCT01873950 Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects Completed Spaulding Clinical Research LLC Phase 1 This study seeks to compare 4 known QT prolonging drugs versus placebo to determine their effects on electrophysiological and other clinical parameters. The underlying purpose is to determine if depolarization and repolarization effects caused by drugs with differing ionic channel mechanisms can be distinguished from one another, and to gauge the sensitivity and specificity of novel signal analyses for detection of depolarization and repolarization changes. Secondarily, to evaluate the exposure response relationship and drug induced effects on the heart rate biomarker relationship.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Dofetilide

Condition Name

Condition Name for Dofetilide
Intervention Trials
Drug-induced QT Prolongation 2
Pharmacokinetics 2
Pharmacodynamics 2
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Condition MeSH

Condition MeSH for Dofetilide
Intervention Trials
Long QT Syndrome 4
Peripheral Arterial Disease 1
Angina Pectoris 1
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Clinical Trial Locations for Dofetilide

Trials by Country

Trials by Country for Dofetilide
Location Trials
United States 18
Czech Republic 1
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Trials by US State

Trials by US State for Dofetilide
Location Trials
Massachusetts 2
Wisconsin 2
Virginia 1
Texas 1
South Carolina 1
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Clinical Trial Progress for Dofetilide

Clinical Trial Phase

Clinical Trial Phase for Dofetilide
Clinical Trial Phase Trials
Phase 4 1
Phase 3 1
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Dofetilide
Clinical Trial Phase Trials
Completed 4
Recruiting 1
Suspended 1
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Clinical Trial Sponsors for Dofetilide

Sponsor Name

Sponsor Name for Dofetilide
Sponsor Trials
Spaulding Clinical Research LLC 3
Food and Drug Administration (FDA) 3
Oregon Health and Science University 1
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Sponsor Type

Sponsor Type for Dofetilide
Sponsor Trials
Other 8
U.S. Fed 4
Industry 2
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Serving hundreds of leading biopharmaceutical companies globally:

Deloitte
Baxter
Farmers Insurance
Mallinckrodt
Chinese Patent Office
Medtronic
Queensland Health
AstraZeneca
Argus Health

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