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Last Updated: October 21, 2019

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CLINICAL TRIALS PROFILE FOR DIPRIVAN

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Clinical Trials for Diprivan

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00446420 Cognitive Impairment Following Sedation for Colonoscopy With Propofol, Midazolam and Fentanyl Combinations Completed Melbourne Health Phase 4 2007-02-01 Our hypothesis is that adding midazolam and/or fentanyl to propofol sedation for elective outpatient colonoscopy increases cognitive impairment at hospital discharge without improving intraoperative conditions or reducing intraoperative side-effects. 200 healthy patients aged 18 years or older will be randomised to receive propofol or propofol plus midazolam and/or fentanyl. Cognitive impairment will be tested at hospital discharge using Cogstate computerised testing software.
NCT00616759 The Effect on Cognition of Terminating ECT Induced Seizures With Propofol Completed Loma Linda University N/A 2006-09-01 Participating subjects are those who are referred for electroconvulsive therapy (ECT) for severe depression who have agreed to the protocol. The control group receives ECT as usual. The other group receives propofol to terminate the ECT-induced seizure timed so that the seizure lasts at least 25 seconds. Extensive neuropsychological testing is being done on both groups before beginning ECT and within 48 hours after the 6th treatment. Multiple markers of the rapidity of recovery from anesthesia are being obtained from all subjects for 6 ECTs.
NCT00676416 Influence of Propofol on Alveolar Macrophage in Asthmatic Patients Completed HRSA/Maternal and Child Health Bureau Phase 4 2008-04-01 The change of airway responsiveness and alveolar macrophage (AM) immunity occurs during the pathogenesis of asthma. Macrophage-associated airway protection in patients with asthma is affected positively or negatively by propofol general anesthesia. The investigators hypothesized that the effects of propofol on asthmatic AMs and corresponding airway reactivity in vivo is different from the in vitro research. Through in vivo airway hyperresponsiveness (AHR) observation and clinical investigation of AM immune functions from asthma patients undergoing propofol general anesthesia to clarify the precise effects of propofol on AM immunity, and to provide theoretical basis for the clinical administration of propofol in asthmatic patients. This would optimize the practice of clinical anesthesia, especially for those with the tendency of AHR.
NCT00676416 Influence of Propofol on Alveolar Macrophage in Asthmatic Patients Completed Nanjing Medical University Phase 4 2008-04-01 The change of airway responsiveness and alveolar macrophage (AM) immunity occurs during the pathogenesis of asthma. Macrophage-associated airway protection in patients with asthma is affected positively or negatively by propofol general anesthesia. The investigators hypothesized that the effects of propofol on asthmatic AMs and corresponding airway reactivity in vivo is different from the in vitro research. Through in vivo airway hyperresponsiveness (AHR) observation and clinical investigation of AM immune functions from asthma patients undergoing propofol general anesthesia to clarify the precise effects of propofol on AM immunity, and to provide theoretical basis for the clinical administration of propofol in asthmatic patients. This would optimize the practice of clinical anesthesia, especially for those with the tendency of AHR.
NCT00788008 Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly Completed VA Office of Research and Development N/A 2008-11-01 The purpose of this research is to determine if post-operative cognition will be better if the general anesthesia for surgery is done with an inhaled (gas through a breathing tube) or intravenous (medicine injected in the IV) general anesthetic technique.
NCT00788008 Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly Completed Duke University N/A 2008-11-01 The purpose of this research is to determine if post-operative cognition will be better if the general anesthesia for surgery is done with an inhaled (gas through a breathing tube) or intravenous (medicine injected in the IV) general anesthetic technique.
NCT00854178 Toxicogenomic and Immunocytotoxic Effects of Propofol and Isoflurane Anesthetics in Patients Undergoing Elective Surgery Completed Fundação de Amparo à Pesquisa do Estado de São Paulo Phase 4 2008-03-01 The purpose of this study is to evaluate if the anesthetics propofol and isoflurane can damage DNA, induce apoptosis, change expression of genes related to apoptosis and DNA repair and change cytokines profile in patients submitted to elective surgery.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Diprivan

Condition Name

Condition Name for Diprivan
Intervention Trials
Anesthesia 4
Obesity 3
Treatment Resistant Depression 2
Major Depression 1
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Condition MeSH

Condition MeSH for Diprivan
Intervention Trials
Sleep Apnea Syndromes 4
Sleep Apnea, Obstructive 3
Seizures 2
Depressive Disorder, Treatment-Resistant 2
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Clinical Trial Locations for Diprivan

Trials by Country

Trials by Country for Diprivan
Location Trials
United States 13
Egypt 3
Canada 2
Korea, Republic of 2
China 1
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Trials by US State

Trials by US State for Diprivan
Location Trials
California 3
Georgia 2
New York 2
Pennsylvania 1
Utah 1
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Clinical Trial Progress for Diprivan

Clinical Trial Phase

Clinical Trial Phase for Diprivan
Clinical Trial Phase Trials
Phase 4 15
Phase 3 5
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for Diprivan
Clinical Trial Phase Trials
Completed 19
Recruiting 10
Not yet recruiting 3
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Clinical Trial Sponsors for Diprivan

Sponsor Name

Sponsor Name for Diprivan
Sponsor Trials
Cairo University 2
Emory University 2
Asan Medical Center 2
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Sponsor Type

Sponsor Type for Diprivan
Sponsor Trials
Other 49
Industry 6
U.S. Fed 3
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