Study to Compare the Pharmacokinetics of IV Diclofenac Sodium (2 Doses)Versus Oral Diclofenac Potassium
The purpose of this study is to assess the pharmacokinetic parameters of intravenous
diclofenac sodium (DIC075V) 18.75 mg and 37.5 mg following single- and multiple-dose
administration, as compared to oral diclofenac potassium (Cataflam® 50 mg), the approved
Oral Diclofenac for Retinal Photocoagulation in Diabetic Retinopathy
University of Sao Paulo
The purpose of this study was to evaluate the analgesic effect of oral potassium diclofenac
in patients with proliferative diabetic retinopathy submitted to retinal photocoagulation.
Two groups of patients were followed and the effect of the treatment (diclofenac plus laser)
was compared to placebo (placebo plus laser). Pain associated with treatment was recorded
using a Visual Analog Scale 15 minutes after the procedure.
Efficacy of Diclofenac Potassium Versus Acetaminophen in Febrile Children With Acute Upper Respiratory Tract Infections
The purpose of this study is to assess if a single dose of Diclofenac potassium (0.5 mg/kg)
is more or as effective as a single dose of Acetaminophen (10 mg/kg) in the reduction of
fever during 2 hours, in the treatment of febrile children with acute upper respiratory
This is a comparative double blind, double dummy, randomized study on the effectiveness of
Diclofenac potassium versus Acetaminophen in febrile children with acute upper respiratory
tract infections. The patient will be randomized to either group: Group A (Diclofenac
potassium (0.5 mg/kg) or Group B (Acetaminophen (10 mg/kg)). A Health Care Professional
trained will measure the temperature during 2 hours. During the study period, parents or
legal representatives will be invited to fill a survey about the habits and knowledge
regarding fever management at home.
Efficacy of Diclofenac Potassium vs Nimesulide in the Treatment of Fever and Pain in Children With Upper Respiratory Tract Infection
This is a local, phase IV, open-label, randomized, head to head study of children aged 3 to 7
years. The objective of the study is to compare the efficacy of a single dose of both
diclofenac potassium and nimesulide in the reduction of fever and pain secondary to upper
respiratory tract infection.
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