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Generated: December 19, 2018

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CLINICAL TRIALS PROFILE FOR DICLOFENAC

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Clinical Trials for Diclofenac

Trial ID Title Status Sponsor Phase Summary
NCT00090181 Study of MK0663 in Patients With Chronic Low Back Pain (0663-806)(COMPLETED) Completed Merck Sharp & Dohme Corp. Phase 4 The purpose of this study is to evaluate the efficacy of MK0663 for the treatment of chronic low back pain and to investigate the overall safety and tolerability over four weeks of treatment.
NCT00092378 A Study of Two Approved Drugs in the Treatment of Post-Bunionectomy Surgery Pain (0966-234)(COMPLETED) Completed Merck Sharp & Dohme Corp. Phase 3 This purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following bunionectomy surgery.
NCT00092703 Investigational Drug Versus an Approved Drug in Patients With Osteoarthritis (0663-061)(COMPLETED) Completed Merck Sharp & Dohme Corp. Phase 3 The purpose of this study is to compare the gastrointestinal tolerability of an investigational drug to an approved drug in the treatment of osteoarthritis during one year treatment period.
NCT00092742 Investigational Drug Versus an Approved Drug in Patients With Rheumatoid Arthritis (0663-072) Completed Merck Sharp & Dohme Corp. Phase 3 The purpose of this study is to evaluate the long-term safety of an investigational drug versus an approved drug for the relief of pain in patients with rheumatoid arthritis.
NCT00108992 Efficacy and Safety of Topical Diclofenac Combined With Oral Diclofenac in the Treatment of Knee Osteoarthritis Completed Nuvo Research Inc. Phase 3 Oral non-steroidal anti-inflammatory drugs (NSAIDs) are a recommended treatment for the symptoms of osteoarthritis of the knee. However, NSAIDs may cause a range of negative side effects, including stomach pain, heartburn, bleeding stomach ulcer, and liver or kidney abnormality. A topical NSAID may relieve pain and other symptoms of osteoarthritis of the knee, while minimizing the side effects common to oral NSAIDs. The purpose of this study is to determine the safety and effectiveness of a topical NSAID when used alone or when combined with an oral NSAID in the treatment of osteoarthritis of the knee.
NCT00121901 Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis? Completed Hvidovre University Hospital Phase 3 Post-ERCP pancreatitis can be a serious complication to ERCP. Two studies have shown a promising preventive effect of glyceryl nitrate. This study should provide a final answer to the clinical question: Does glyceryl nitrate prevent post-ERCP pancreatitis? The study is a prospective, randomized, double blind, placebo-controlled multicenter trial. The investigators intend to include 1600 patients from Norway, Sweden, Denmark, and France. The patients will receive either placebo or a glyceryl nitrate patch (15 mg/24 hours). Follow-up will occur after 7 days. The primary outcome measure will be post-ERCP pancreatitis, and secondary outcome measures will be mild, moderate and severe pancreatitis; post procedure pancreatitis-related mortality; and adverse events.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Diclofenac

Condition Name

Condition Name for Diclofenac
Intervention Trials
Pain 43
Osteoarthritis 21
Postoperative Pain 11
Pain, Postoperative 11
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Condition MeSH

Condition MeSH for Diclofenac
Intervention Trials
Osteoarthritis 48
Pain, Postoperative 35
Osteoarthritis, Knee 31
Sprains and Strains 13
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Clinical Trial Locations for Diclofenac

Trials by Country

Trials by Country for Diclofenac
Location Trials
United States 364
United Kingdom 48
Germany 33
India 30
Brazil 29
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Trials by US State

Trials by US State for Diclofenac
Location Trials
Texas 29
Florida 24
California 21
Pennsylvania 17
Alabama 16
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Clinical Trial Progress for Diclofenac

Clinical Trial Phase

Clinical Trial Phase for Diclofenac
Clinical Trial Phase Trials
Phase 4 94
Phase 3 84
Phase 2/Phase 3 12
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Clinical Trial Status

Clinical Trial Status for Diclofenac
Clinical Trial Phase Trials
Completed 189
Recruiting 56
Unknown status 24
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Clinical Trial Sponsors for Diclofenac

Sponsor Name

Sponsor Name for Diclofenac
Sponsor Trials
Novartis 18
Merck Sharp & Dohme Corp. 13
Pfizer 12
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Sponsor Type

Sponsor Type for Diclofenac
Sponsor Trials
Other 244
Industry 153
U.S. Fed 4
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Serving hundreds of leading biopharmaceutical companies globally:

Chubb
Chinese Patent Office
Queensland Health
Healthtrust
Fuji
Harvard Business School
Merck
US Army
Fish and Richardson

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