Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury
Completed
National Heart, Lung, and Blood Institute (NHLBI)
N/A
2003-04-01
The purpose of this study is to evaluate the clinical outcome of patients following blunt
traumatic injury with hypovolemic shock, who receive either lactated ringer's solution or
hypertonic saline with dextran (HSD) resuscitation; also, to focus specifically on neurologic
outcome in patients with brain injury and on the effect of HSD resuscitation on inflammatory
cell responsiveness.
Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury
Completed
University of Washington
N/A
2003-04-01
The purpose of this study is to evaluate the clinical outcome of patients following blunt
traumatic injury with hypovolemic shock, who receive either lactated ringer's solution or
hypertonic saline with dextran (HSD) resuscitation; also, to focus specifically on neurologic
outcome in patients with brain injury and on the effect of HSD resuscitation on inflammatory
cell responsiveness.
To compare hypertonic saline to Lactated Ringer's solution and assess whether one speeds up
the process of getting rid of extra body water faster in women with preeclampsia.
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