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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR DECASPRAY


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All Clinical Trials for Decaspray

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00895245 ↗ Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy Terminated National Cancer Institute (NCI) Phase 2 2009-02-01 RATIONALE: Fosaprepitant dimeglumine, palonosetron hydrochloride, and dexamethasone may help lessen or prevent nausea and vomiting caused by cisplatin in patients with head and neck cancer undergoing chemotherapy and radiation therapy. PURPOSE: This phase II trial is studying how well fosaprepitant dimeglumine together with palonosetron hydrochloride and dexamethasone works in preventing nausea and vomiting caused by cisplatin in patients with stage III or stage IV head and neck cancer undergoing chemotherapy and radiation therapy.
NCT00895245 ↗ Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy Terminated University of Washington Phase 2 2009-02-01 RATIONALE: Fosaprepitant dimeglumine, palonosetron hydrochloride, and dexamethasone may help lessen or prevent nausea and vomiting caused by cisplatin in patients with head and neck cancer undergoing chemotherapy and radiation therapy. PURPOSE: This phase II trial is studying how well fosaprepitant dimeglumine together with palonosetron hydrochloride and dexamethasone works in preventing nausea and vomiting caused by cisplatin in patients with stage III or stage IV head and neck cancer undergoing chemotherapy and radiation therapy.
NCT01049945 ↗ Bendamustine Hydrochloride, Lenalidomide, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma Completed Mayo Clinic Phase 1/Phase 2 2010-02-01 RATIONALE: Drugs used in chemotherapy, such as bendamustine hydrochloride and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Lenalidomide may stimulate the immune system in different ways and stop cancer cells from growing. Giving bendamustine hydrochloride together with lenalidomide and dexamethasone may kill more cancer cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of bendamustine hydrochloride and lenalidomide when given together with dexamethasone and to see how well they work in treating patients with relapsed multiple myeloma.
NCT01057225 ↗ Cyclophosphamide, Carfilzomib, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed Active Multiple Myeloma Completed Mayo Clinic Phase 1/Phase 2 2010-03-01 RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Thalidomide may stop the growth of cancer cells by blocking blood flow to the tumor. Giving combination chemotherapy together with carfilzomib and thalidomide may kill more cancer cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of carfilzomib when given together with cyclophosphamide, thalidomide, and dexamethasone in treating patients with newly diagnosed active multiple myeloma.
NCT01072773 ↗ Bortezomib, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Light Chain Amyloidosis Completed Mayo Clinic Phase 2 2010-03-01 RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as cyclophosphamide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving bortezomib together with combination chemotherapy may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving bortezomib, cyclophosphamide, and dexamethasone together works in treating patients with primary systemic light chain amyloidosis.
NCT01155583 ↗ Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Relapsed or Refractory Multiple Myeloma Completed National Cancer Institute (NCI) Phase 1/Phase 2 2010-06-01 RATIONALE: Drugs used in chemotherapy, such as azacitidine and dexamethasone, work in different ways to stop the growth of cancer cells either by killing the cells or by stopping them from dividing. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Giving azacitidine together with lenalidomide and dexamethasone may kill more cancer cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of azacitidine when given together with lenalidomide and low-dose dexamethasone in treating patients with relapsed or refractory multiple myeloma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Decaspray

Condition Name

Condition Name for Decaspray
Intervention Trials
Refractory Multiple Myeloma 3
Multiple Myeloma 2
Stage III Squamous Cell Carcinoma of the Oropharynx 1
Nausea and Vomiting 1
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Condition MeSH

Condition MeSH for Decaspray
Intervention Trials
Neoplasms, Plasma Cell 5
Multiple Myeloma 5
Carcinoma, Squamous Cell 1
Oropharyngeal Neoplasms 1
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Clinical Trial Locations for Decaspray

Trials by Country

Trials by Country for Decaspray
Location Trials
United States 23
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Trials by US State

Trials by US State for Decaspray
Location Trials
Minnesota 5
Arizona 2
Missouri 2
Florida 2
California 2
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Clinical Trial Progress for Decaspray

Clinical Trial Phase

Clinical Trial Phase for Decaspray
Clinical Trial Phase Trials
Phase 2 3
Phase 1/Phase 2 4
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Clinical Trial Status

Clinical Trial Status for Decaspray
Clinical Trial Phase Trials
Completed 5
Terminated 1
Active, not recruiting 1
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Clinical Trial Sponsors for Decaspray

Sponsor Name

Sponsor Name for Decaspray
Sponsor Trials
Mayo Clinic 4
National Cancer Institute (NCI) 3
University of Washington 1
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Sponsor Type

Sponsor Type for Decaspray
Sponsor Trials
Other 8
NIH 3
Industry 1
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