CLINICAL TRIALS PROFILE FOR CUROSURF

All Clinical Trials for Curosurf

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00501982 ↗	Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Study	Completed	Chiesi Farmaceutici S.p.A.	Phase 4	2007-03-01	The primary objective of this study is to compare two methods of post-delivery stabilization and subsequent early respiratory care for reducing the need for MV and related secondary complications, such as BPD, in premature babies at high risk of RDS: 1. Early stabilization on nCPAP 2. Intubation, prophylactic surfactant (Curosurf®) administration shortly after delivery, and rapid extubation to nCPAP. The data obtained from this comparison will be applied to test the hypothesis that preterm neonates at risk of RDS who are treated with prophylactic surfactant + nCPAP show less need for MV when compared to infants who receive nCPAP alone.
NCT00751959 ↗	Surfactant Application During Spontaneous Breathing With Continuous Positive Airway Pressure (CPAP) in Premature Infants < 27 Weeks	Completed	Altona Children's Hospital	N/A	2009-04-01	This study investigates the efficacy of surfactant application during spontaneous breathing with CPAP in avoiding death and chronic lung disease (CLD) in very immature infants with a gestational age of less than 27 weeks.
NCT00751959 ↗	Surfactant Application During Spontaneous Breathing With Continuous Positive Airway Pressure (CPAP) in Premature Infants < 27 Weeks	Completed	Asklepios Kliniken Hamburg GmbH	N/A	2009-04-01	This study investigates the efficacy of surfactant application during spontaneous breathing with CPAP in avoiding death and chronic lung disease (CLD) in very immature infants with a gestational age of less than 27 weeks.
NCT00751959 ↗	Surfactant Application During Spontaneous Breathing With Continuous Positive Airway Pressure (CPAP) in Premature Infants < 27 Weeks	Completed	Charite University, Berlin, Germany	N/A	2009-04-01	This study investigates the efficacy of surfactant application during spontaneous breathing with CPAP in avoiding death and chronic lung disease (CLD) in very immature infants with a gestational age of less than 27 weeks.
NCT00751959 ↗	Surfactant Application During Spontaneous Breathing With Continuous Positive Airway Pressure (CPAP) in Premature Infants < 27 Weeks	Completed	DRK Kinderklinik Siegen	N/A	2009-04-01	This study investigates the efficacy of surfactant application during spontaneous breathing with CPAP in avoiding death and chronic lung disease (CLD) in very immature infants with a gestational age of less than 27 weeks.

Clinical Trial Conditions for Curosurf

Condition Name

Condition Name for Curosurf
Intervention	Trials
Respiratory Distress Syndrome	11
Respiratory Distress Syndrome, Newborn	6
Bronchopulmonary Dysplasia	5
Hyaline Membrane Disease	1

Condition MeSH

Condition MeSH for Curosurf
Intervention	Trials
Respiratory Distress Syndrome	22
Respiratory Distress Syndrome, Newborn	22
Respiratory Distress Syndrome, Adult	19
Syndrome	13

Clinical Trial Locations for Curosurf

Trials by Country

Trials by Country for Curosurf
Location	Trials
United States	40
Italy	20
France	3
Czech Republic	1
Germany	1

Trials by US State

Trials by US State for Curosurf
Location	Trials
Michigan	4
Massachusetts	3
Illinois	3
Missouri	2
Texas	2

Clinical Trial Progress for Curosurf

Clinical Trial Phase

Clinical Trial Phase for Curosurf
Clinical Trial Phase	Trials
Phase 4	8
Phase 3	3
Phase 2/Phase 3	1

Clinical Trial Status

Clinical Trial Status for Curosurf
Clinical Trial Phase	Trials
Completed	9
Recruiting	6
Unknown status	4

Clinical Trial Sponsors for Curosurf

Sponsor Name

Sponsor Name for Curosurf
Sponsor	Trials
Chiesi Farmaceutici S.p.A.	7
University of Florence	2
University of Michigan	2

Sponsor Type

Sponsor Type for Curosurf
Sponsor	Trials
Other	58
Industry	12