CLINICAL TRIALS PROFILE FOR CORDARONE

All Clinical Trials for Cordarone

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00300495 ↗	Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection	Terminated	Beth Israel Deaconess Medical Center	Phase 3	2006-02-01	Atrial fibrillation is a very common complication of pulmonary resection. Patients who develop atrial fibrillation require additional treatment and are more likely to stay in the hospital for longer period of time increasing the costs associated with the operation. We propose a randomized controlled trial to see if oral amiodarone given for one week before surgery can prevent atrial fibrillation after pulmonary resection. We plan to evaluate the incidence of atrial fibrillation in patients who received preoperative amiodarone and compare them to the incidence of atrial fibrillation in patients who did not received preoperative amiodarone.
NCT00420953 ↗	Relative Bioavailability of PM101 IV and Cordarone IV	Completed	Prism Pharmaceuticals	Phase 1	2006-12-18	Determine the relative bioavailability of PM101 I.V. and Cordarone I.V.
NCT00578617 ↗	Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial	Completed	Abbott Medical Devices	N/A	2006-09-01	The CABANA pilot study is designed to test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose of the elimination of atrial fibrillation (AF) is superior to current state-of-the-art therapy with either rate control or anti-arrhythmic drugs for reducing AF recurrences at 1 year follow-up.
NCT00578617 ↗	Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial	Completed	Duke Clinical Research Institute	N/A	2006-09-01	The CABANA pilot study is designed to test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose of the elimination of atrial fibrillation (AF) is superior to current state-of-the-art therapy with either rate control or anti-arrhythmic drugs for reducing AF recurrences at 1 year follow-up.
NCT00578617 ↗	Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial	Completed	St. Jude Medical	N/A	2006-09-01	The CABANA pilot study is designed to test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose of the elimination of atrial fibrillation (AF) is superior to current state-of-the-art therapy with either rate control or anti-arrhythmic drugs for reducing AF recurrences at 1 year follow-up.
NCT00578617 ↗	Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial	Completed	Mayo Clinic	N/A	2006-09-01	The CABANA pilot study is designed to test the hypothesis that the treatment strategy of percutaneous left atrial catheter ablation for the purpose of the elimination of atrial fibrillation (AF) is superior to current state-of-the-art therapy with either rate control or anti-arrhythmic drugs for reducing AF recurrences at 1 year follow-up.
NCT00587483 ↗	Amiodarone for the Prevention of Reperfusion Ventricular Fibrillation	Completed	Mayo Clinic	N/A	2007-11-01	This was a prospective, randomized, double blinded study in which patients undergoing a cardiopulmonary bypass (CPB) with aortic cross clamping were randomly assigned to receive amiodarone, lidocaine, or saline placebo prior to removal of the aortic cross clamp. (CPB is a technique that temporarily takes over the function of the heart and lungs during surgery, maintaining the circulation of blood and the oxygen content of the body.) Specifically, we will test the hypothesis that amiodarone is superior to both lidocaine and placebo in the prevention of a severely abnormal heart rhythm when the blood flow is restored to the heart after the aortic cross clamp is removed.

Clinical Trial Conditions for Cordarone

Condition Name

Condition Name for Cordarone
Intervention	Trials
Atrial Fibrillation	13
Heart Failure	2
New Onset Atrial Fibrillation	2
Ventricular Tachycardia	2

Condition MeSH

Condition MeSH for Cordarone
Intervention	Trials
Atrial Fibrillation	19
Tachycardia, Ventricular	4
Tachycardia	4
Myocardial Ischemia	2

Clinical Trial Locations for Cordarone

Trials by Country

Trials by Country for Cordarone
Location	Trials
United States	63
Canada	13
Australia	4
France	4
Poland	3

Trials by US State

Trials by US State for Cordarone
Location	Trials
Pennsylvania	5
New York	4
Minnesota	4
Virginia	3
Oregon	3

Clinical Trial Progress for Cordarone

Clinical Trial Phase

Clinical Trial Phase for Cordarone
Clinical Trial Phase	Trials
Phase 4	9
Phase 3	7
Phase 2	2

Clinical Trial Status

Clinical Trial Status for Cordarone
Clinical Trial Phase	Trials
Completed	10
Terminated	8
Unknown status	4

Clinical Trial Sponsors for Cordarone

Sponsor Name

Sponsor Name for Cordarone
Sponsor	Trials
Abbott Medical Devices	3
St. Jude Medical	3
Mayo Clinic	3

Sponsor Type

Sponsor Type for Cordarone
Sponsor	Trials
Other	32
Industry	16
NIH	3