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CLINICAL TRIALS PROFILE FOR CONIVAPTAN HYDROCHLORIDE

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Clinical Trials for Conivaptan Hydrochloride

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00057356	Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure	Completed	Cumberland Pharmaceuticals	Phase 2	This is a randomized, double-blind, placebo-controlled, dose ranging pilot study to examine the effects of conivaptan in patients with acute decompensated heart failure.
NCT00379847	An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia	Completed	Cumberland Pharmaceuticals	Phase 3	This study will investigate the application of a vasopressin antagonist in the treatment of hyponatremia most likely caused by inappropriate AVP secretion. The population studied will include patients with euvolemic or hypervolemic hyponatremia.
NCT00435591	A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia	Completed	Cumberland Pharmaceuticals	Phase 4	The study will evaluate the effectiveness and safety of multiple dosing regimens of IV conivaptan in subjects with euvolemic or hypervolemic hyponatremia
NCT00478192	Study of Efficacy & Safety for 3 Infusion Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia	Completed	Cumberland Pharmaceuticals	Phase 3	The study is designed to assess the efficacy and safety of multiple infusions of conivaptan in subjects with euvolemic or hypervolemic hyponatremia
NCT00592475	A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients	Completed	Cumberland Pharmaceuticals	Phase 2	To evaluate the safety of IV conivaptan in stable euvolemic or hypervolemic cirrhotic patients, and to characterize the effects of IV conivaptan on the hepatic hemodynamic response in patients with cirrhosis.

Clinical Trial Conditions for Conivaptan Hydrochloride

Condition Name

Condition Name for Conivaptan Hydrochloride
Intervention	Trials
Hyponatremia	9
Heart Failure	3
Cerebral Edema	2
Liver Disease	2

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Condition MeSH

Condition MeSH for Conivaptan Hydrochloride
Intervention	Trials
Hyponatremia	9
Heart Failure	6
Brain Edema	2
Liver Diseases	2

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Clinical Trial Locations for Conivaptan Hydrochloride

Trials by Country

Trials by Country for Conivaptan Hydrochloride
Location	Trials
United States	49
India	3
Israel	2
South Africa	1
Colombia	1

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Trials by US State

Trials by US State for Conivaptan Hydrochloride
Location	Trials
Colorado	4
New York	4
Florida	4
California	4
South Carolina	4

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Clinical Trial Progress for Conivaptan Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Conivaptan Hydrochloride
Clinical Trial Phase	Trials
Phase 4	4
Phase 3	5
Phase 2	3

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Clinical Trial Status

Clinical Trial Status for Conivaptan Hydrochloride
Clinical Trial Phase	Trials
Completed	10
Withdrawn	4
Terminated	3

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Clinical Trial Sponsors for Conivaptan Hydrochloride

Sponsor Name

Sponsor Name for Conivaptan Hydrochloride
Sponsor	Trials
Cumberland Pharmaceuticals	10
Astellas Pharma Inc	3
University of Florida	1

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Sponsor Type

Sponsor Type for Conivaptan Hydrochloride
Sponsor	Trials
Industry	14
Other	10

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