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Generated: December 12, 2018

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CLINICAL TRIALS PROFILE FOR COMBIVENT

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Clinical Trials for Combivent

Trial ID Title Status Sponsor Phase Summary
NCT00096616 Combivent® CFC Metered Dose Inhaler (MDI) in Moderate to Severe Asthma Completed Boehringer Ingelheim Phase 2 The purpose of this study is to demonstrate the superior bronchodilator efficacy of inhaled Combivent® CFC MDI vs. Albuterol HFA MDI in moderate to severe asthma patients.
NCT00273962 A Comparison of Combivent UDV (Ipratropium 500mcg and Salbutamol 2.5mg) and Salbutamol UDV Alone (2.5mg) Completed Boehringer Ingelheim Phase 4 To compare the bronchodilator efficacy of ipratropium plus salbutamol (Combivent) with salbutamol alone given every 20 minutes for three doses in asthmatic children with severe acute exacerbation
NCT00354354 Bronchodilators and Oxygen Kinetics With Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients Completed Queen's University Phase 4 Hypothesis: The reduction of dynamic hyperinflation and its negative effects on the respiratory system following a bronchodilator could lead to an improvement of cardiac function in terms of increased cardiac output. This may enhance oxygen delivery to the exercising muscles in COPD patients. Bronchodilator administration may also have an indirect effect on V'O2 kinetics via its action on cardiovascular and pulmonary variables. Objectives: 1. To evaluate the effects of a bronchodilators on V'E , V'CO2 , and V'O2 kinetics in COPD during constant work-rate cycle exercise, and to evaluate whether bronchodilators will accelerate, indirectly, phase 2 kinetics (usually slower in COPD patients than normal subjects) and shorten t for V'E, V'CO2 , and V'O2 and shorten half-times for HR and O2 pulse, thus showing an improvement of oxygen transport to the peripheral active muscles. 2. To determine the impact of a bronchodilator-induced reduction in dynamic hyperinflation, and its effects on cardiovascular and pulmonary function, on exercise limitation in COPD.
NCT00359788 A Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent Inhalation Aerosol in COPD Patients. Completed Boehringer Ingelheim Phase 4 The objective of this study is to evaluate the efficacy and safety of 12 weeks treatment with tiotropium HandiHaler 18 micrograms (mcg) daily compared to Combivent Metered Dose Inhaler (MDI) Chlorofluorocarbon Inhalation Aerosol 2 actuations four times a day in Chronic Obstructive Pulmonary Disease (COPD) patients currently prescribed Combivent® MDI.
NCT00388882 Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent® Inhalation Aerosol in COPD Patients. Completed Boehringer Ingelheim Phase 4 The objective of this study is to evaluate the efficacy and safety of 12 weeks treatment with tiotro pium HandiHaler® 18 mcg daily compared to Combivent® MDI CFC Inhalation Aerosol 2 actuations qid in COPD patients currently prescribed Combivent® MDI.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Combivent

Condition Name

Condition Name for Combivent
Intervention Trials
Pulmonary Disease, Chronic Obstructive 9
Asthma 5
Chronic Obstructive Pulmonary Disease 4
Healthy 1
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Condition MeSH

Condition MeSH for Combivent
Intervention Trials
Pulmonary Disease, Chronic Obstructive 14
Lung Diseases 14
Chronic Disease 9
Lung Diseases, Obstructive 8
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Clinical Trial Locations for Combivent

Trials by Country

Trials by Country for Combivent
Location Trials
United States 145
China 9
Argentina 2
United Kingdom 2
Canada 2
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Trials by US State

Trials by US State for Combivent
Location Trials
Texas 7
Colorado 7
California 7
South Carolina 7
Idaho 6
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Clinical Trial Progress for Combivent

Clinical Trial Phase

Clinical Trial Phase for Combivent
Clinical Trial Phase Trials
Phase 4 9
Phase 3 6
Phase 2 4
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Clinical Trial Status

Clinical Trial Status for Combivent
Clinical Trial Phase Trials
Completed 13
Terminated 4
Unknown status 2
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Clinical Trial Sponsors for Combivent

Sponsor Name

Sponsor Name for Combivent
Sponsor Trials
Boehringer Ingelheim 15
Queen's University 2
Novartis 1
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Sponsor Type

Sponsor Type for Combivent
Sponsor Trials
Other 21
Industry 17
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Serving hundreds of leading biopharmaceutical companies globally:

Covington
Fuji
Citi
Fish and Richardson
Farmers Insurance
Chubb
Mallinckrodt
Chinese Patent Office
Argus Health

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