Phase II Randomized Study of Intravenous Versus Oral Clomipramine in Patients With Obsessive Compulsive Disorder
Unknown status
Stanford University
Phase 2
1999-10-01
OBJECTIVES:
I. Evaluate the efficacy of intravenous versus oral pulse loading of clomipramine (CMI)
followed by a 12-week course of maintenance therapy in patients with obsessive compulsive
disorder.
Phase II Randomized Study of Intravenous Versus Oral Clomipramine in Patients With Obsessive Compulsive Disorder
Unknown status
National Center for Research Resources (NCRR)
Phase 2
1999-10-01
OBJECTIVES:
I. Evaluate the efficacy of intravenous versus oral pulse loading of clomipramine (CMI)
followed by a 12-week course of maintenance therapy in patients with obsessive compulsive
disorder.
Quetiapine Augmentation in Severe Obsessive Compulsive Disorder
Completed
AstraZeneca
Phase 3
2002-04-01
The purpose of the study is to evaluate the efficacy of quetiapine or placebo added to
baseline treatment of SSRI/clomipramine for the treatment of OCD in adult subjects.
Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment
Completed
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Phase 4
2007-05-01
This will be a controlled, randomized, double-blind and double-dummy study on the treatment
augmentation strategy for obsessive compulsive disorder patients non-respondent to first line
pharmacological treatment. The investigators will compare: fluoxetine maintenance at maximum
dosage for additional 12 weeks; the association of fluoxetine with quetiapine; and the
association of fluoxetine with clomipramine.
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