The scalp is one of the most common affected sites in psoriatic patients as 79% of them have
scalp involvement.It has also a psychological aspect with 31% of patients with scalp
psoriasis indicating distress.
Topical agents remain the mainstay of treatment for scalp psoriasis. However, they are not
always ideal because they might be inconvenient and messy to use, stain or damage hair.
The test shampoo, Clobetasol propionate Shampoo 0.05% (marketed in the USA under the
tradename of Clobex®) was developed to provide the strongest available corticosteroid as a
short-contact therapy in order to improve the chances of it being effective and reduce the
potential for traditional side-effects.
The objective of this study is to compare subject's overall preference between Clobetasol
propionate shampoo 0.05% and three other topical corticosteroids in the treatment of
moderate to severe scalp psoriasis.
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