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Generated: September 17, 2019

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CLINICAL TRIALS PROFILE FOR CLEVIDIPINE

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Clinical Trials for Clevidipine

Trial ID Title Status Sponsor Phase Summary
NCT00093249 Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1) Completed The Medicines Company Phase 3 The purpose of this study is to determine the efficacy of clevidipine injection versus placebo in treating preoperative hypertension.
NCT00093262 Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2) Completed The Medicines Company Phase 3 The purpose of this study is to establish the efficacy of of clevidipine versus placebo in treating postoperative hypertension. Approximately 100 patients with postoperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or placebo.
NCT00093886 Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG) Completed The Medicines Company Phase 3 The purpose of this study is to establish the safety of clevidipine in the treatment of perioperative hypertension. Approximately 500-900 patients with perioperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or nitroglycerin.
NCT00093912 Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP) Completed The Medicines Company Phase 3 The purpose of this study is to establish the safety of clevidipine in the treatment of perioperative hypertension. Approximately 250-500 patients with perioperative hypertension undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or sodium nitroprusside.
NCT00093925 Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC) Completed The Medicines Company Phase 3 The purpose of this study is to establish the safety of clevidipine in the treatment of postoperative hypertension. Approximately 250-500 patients with postoperative hypertension after undergoing coronary artery bypass grafting (CABG), off-pump coronary artery bypass (OPCAB) or minimally invasive direct coronary artery bypass (MIDCAB) surgery and/or valve replacement/repair procedures were anticipated to be randomly assigned to one of two treatment groups: clevidipine or nicardipine.
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Clinical Trial Conditions for Clevidipine

Condition Name

Condition Name for Clevidipine
Intervention Trials
Hypertension 13
Subarachnoid Hemorrhage 2
Cerebral Aneurysm 1
Hypertension, Pulmonary 1
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Condition MeSH

Condition MeSH for Clevidipine
Intervention Trials
Hypertension 11
Hemorrhage 4
Aneurysm 3
Cerebral Hemorrhage 2
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Clinical Trial Locations for Clevidipine

Trials by Country

Trials by Country for Clevidipine
Location Trials
United States 104
Germany 3
Switzerland 1
France 1
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Trials by US State

Trials by US State for Clevidipine
Location Trials
Ohio 9
California 8
Texas 8
Alabama 7
New York 7
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Clinical Trial Progress for Clevidipine

Clinical Trial Phase

Clinical Trial Phase for Clevidipine
Clinical Trial Phase Trials
Phase 4 7
Phase 3 8
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Clevidipine
Clinical Trial Phase Trials
Completed 12
Unknown status 3
Withdrawn 3
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Clinical Trial Sponsors for Clevidipine

Sponsor Name

Sponsor Name for Clevidipine
Sponsor Trials
The Medicines Company 15
Henry Ford Health System 2
New York University School of Medicine 1
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Sponsor Type

Sponsor Type for Clevidipine
Sponsor Trials
Industry 15
Other 10
U.S. Fed 1
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Serving hundreds of leading biopharmaceutical companies globally:

Fuji
Johnson and Johnson
Chinese Patent Office
AstraZeneca
Mallinckrodt
Deloitte

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