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Last Updated: November 27, 2022

CLINICAL TRIALS PROFILE FOR CISPLATIN


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505(b)(2) Clinical Trials for Cisplatin

This table shows clinical trials for potential 505(b)(2) applications. See the next table for all clinical trials
Trial Type Trial ID Title Status Sponsor Phase Start Date Summary
New Combination NCT00003589 ↗ Combination Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer Completed European Organisation for Research and Treatment of Cancer - EORTC Phase 3 1998-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating advanced non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of three different combination chemotherapy regimens in treating patients who have advanced non-small cell lung cancer.
New Combination NCT00130520 ↗ Bevacizumab and Erlotinib Study in Advanced Ovarian Cancer Completed Genentech, Inc. Phase 2 2005-06-01 The purpose of this project is to determine if a new combination of drugs, erlotinib (Tarceva™) and bevacizumab is safe and effective for treating women diagnosed with ovarian cancer whose cancer has progressed while on prior standard chemotherapy treatment with a taxane (paclitaxel or docetaxel) and a platinum (cisplatin or carboplatin).
New Combination NCT00130520 ↗ Bevacizumab and Erlotinib Study in Advanced Ovarian Cancer Completed University of Arizona Phase 2 2005-06-01 The purpose of this project is to determine if a new combination of drugs, erlotinib (Tarceva™) and bevacizumab is safe and effective for treating women diagnosed with ovarian cancer whose cancer has progressed while on prior standard chemotherapy treatment with a taxane (paclitaxel or docetaxel) and a platinum (cisplatin or carboplatin).
>Trial Type >Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for Cisplatin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00001272 ↗ A Phase I Study of Taxol, Cisplatin, Cyclophosphamide and Granulocyte Colony-Stimulating Factor (G-CSF) in Previously Nontreated Ovarian Cancer Patients Completed National Cancer Institute (NCI) Phase 1 1991-09-01 This is a Phase I study which addresses the feasibility and toxicity of adding taxol to the two drug combination which now comprises the standard of care in newly diagnosed advanced stage ovarian cancer, cisplatin and cyclophosphamide. These drugs will be given in a dose intensive fashion with the colony-stimulating factor, G-CSF. Newly diagnosed patients with ovarian cancer will be treated with this regimen to determine the optimal dose of this combination. The pharmacokinetics of taxol and cisplatin DNA-adducts will be studied as well.
NCT00001426 ↗ A Multi-Institutional Phase II Study of Cyclophosphamide, Paclitaxel, Cisplatin With G-CSF for Patients With Newly Diagnosed Advanced Stage Ovarian Cancer Completed National Cancer Institute (NCI) Phase 2 1995-02-03 A supra-additive cytotoxic effect was seen when CAI and paclitaxel were given to human ovarian cancer cells sequentially in tissue culture. We have demonstrated that CAI given for 8 days followed by paclitaxel is reasonably well tolerated and that paclitaxel administration causes a dose-dependent increase in CAI plasma concentration. CAI is a cytostatic drug and continuous exposure is needed. This study will evaluate the combination of continuously administered CAI with three-weekly paclitaxel.
NCT00001427 ↗ A Phase II Trial of 72-Hour Continuous IV Infusion of 9-Aminocamptothecin With G-CSF Support in Patients With Advanced Ovarian Cancer Previously Treated With Paclitaxel and Cisplatin Completed National Cancer Institute (NCI) Phase 2 1995-01-01 The objectives of this study are to determine the response rate to 9-AC in patients with advanced ovarian cancer who have recurrent disease after paclitaxel- and cisplatin-based chemotherapy regimens.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Cisplatin

Condition Name

Condition Name for Cisplatin
Intervention Trials
Head and Neck Cancer 194
Lung Cancer 173
Non-small Cell Lung Cancer 149
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Condition MeSH

Condition MeSH for Cisplatin
Intervention Trials
Carcinoma 738
Lung Neoplasms 718
Carcinoma, Non-Small-Cell Lung 586
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Clinical Trial Locations for Cisplatin

Trials by Country

Trials by Country for Cisplatin
Location Trials
Canada 905
Japan 883
Italy 765
United Kingdom 634
France 615
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Trials by US State

Trials by US State for Cisplatin
Location Trials
New York 572
California 538
Texas 528
Pennsylvania 447
Illinois 436
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Clinical Trial Progress for Cisplatin

Clinical Trial Phase

Clinical Trial Phase for Cisplatin
Clinical Trial Phase Trials
Phase 4 50
Phase 3 764
Phase 2/Phase 3 105
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Clinical Trial Status

Clinical Trial Status for Cisplatin
Clinical Trial Phase Trials
Completed 1507
Recruiting 633
Unknown status 458
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Clinical Trial Sponsors for Cisplatin

Sponsor Name

Sponsor Name for Cisplatin
Sponsor Trials
National Cancer Institute (NCI) 636
Merck Sharp & Dohme Corp. 132
Eli Lilly and Company 115
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Sponsor Type

Sponsor Type for Cisplatin
Sponsor Trials
Other 4740
Industry 1573
NIH 647
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