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CLINICAL TRIALS PROFILE FOR CIMETIDINE

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Clinical Trials for Cimetidine

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00002092	A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection	Completed	Community Research Initiative of New England	N/A	To determine the change in CD4 count after 4 and 8 weeks in HIV-infected patients treated with cimetidine compared to placebo. To observe time-associated trends at weeks 4, 8, 12, and 16 in the change of CD4 counts for patients taking cimetidine for the full 16 weeks. To establish a safety record for cimetidine use in HIV-positive patients.
NCT00002733	Biological Therapy in Treating Patients With Metastatic Cancer	Completed	Hoag Memorial Hospital Presbyterian	Phase 2	RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining different types of biological therapies, including interferon alfa, interleukin-2, and tumor infiltrating lymphocytes, may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of biological therapies, including interferon alfa, interleukin-2, and tumor infiltrating lymphocytes, in treating patients with metastatic cancer.
NCT00038402	Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer	Completed	Genentech, Inc.	Phase 3	The purpose of this study is to evaluate the addition of Herceptin to standard chemotherapy treatment of patients newly diagnosed with operable breast cancer. Other objectives: 1) to evaluate the potential of this therapy to reduce the size of the tumor and increase the possibility of breast conservative surgery, 2) evaluate the ability of this regimen to prevent recurrence of breast cancer and impact on survival, 3) determine side effect profile with the addition of Herceptin, and 4) evaluate significance of HER2 expression by two different methods.

Clinical Trial Conditions for Cimetidine

Condition Name

Condition Name for Cimetidine
Intervention	Trials
Healthy	4
Breast Cancer	3
COPD	2

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Condition MeSH

Condition MeSH for Cimetidine
Intervention	Trials
Carcinoma	4
Breast Neoplasms	3
Rectal Neoplasms	2

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Clinical Trial Locations for Cimetidine

Trials by Country

Trials by Country for Cimetidine
Location	Trials
United States	81
China	5
Germany	4
Ireland	2
Canada	2

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Trials by US State

Trials by US State for Cimetidine
Location	Trials
Texas	14
Florida	4
Pennsylvania	4
Illinois	4
North Carolina	3

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Clinical Trial Progress for Cimetidine

Clinical Trial Phase

Clinical Trial Phase for Cimetidine
Clinical Trial Phase	Trials
Phase 4	7
Phase 3	7
Phase 2	12

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Clinical Trial Status

Clinical Trial Status for Cimetidine
Clinical Trial Phase	Trials
Completed	27
Unknown status	6
Active, not recruiting	5

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Clinical Trial Sponsors for Cimetidine

Sponsor Name

Sponsor Name for Cimetidine
Sponsor	Trials
M.D. Anderson Cancer Center	11
Genentech, Inc.	5
Boehringer Ingelheim	3

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Sponsor Type

Sponsor Type for Cimetidine
Sponsor	Trials
Other	43
Industry	29
U.S. Fed	2

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