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Last Updated: August 13, 2022

CLINICAL TRIALS PROFILE FOR CHOLINE C-11


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All Clinical Trials for Choline C-11

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003410 ↗ Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas Completed National Cancer Institute (NCI) Phase 1 1998-07-01 RATIONALE: New imaging procedures such as the use of gadolinium texaphyrin with MRI may improve the ability to detect the extent of gliomas. PURPOSE: Phase I trial to study the effectiveness of gadolinium texaphyrin used with MRI-guided surgery in treating patients with high-grade glioma.
NCT00003410 ↗ Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas Completed Jonsson Comprehensive Cancer Center Phase 1 1998-07-01 RATIONALE: New imaging procedures such as the use of gadolinium texaphyrin with MRI may improve the ability to detect the extent of gliomas. PURPOSE: Phase I trial to study the effectiveness of gadolinium texaphyrin used with MRI-guided surgery in treating patients with high-grade glioma.
NCT00004697 ↗ Randomized Study of the Use of Intravenous Choline Supplementation in Long Term Total Parenteral Nutrition Completed University of Texas N/A 1997-11-01 OBJECTIVES: I. Determine whether intravenous choline supplementation will reverse the hepatic steatosis and improve liver function in patients who receive long term total parenteral nutrition.
NCT00006061 ↗ Study of Phosphatidylcholine in a Patient With Methionine Adenosyltransferase Deficiency Completed UNC Lineberger Comprehensive Cancer Center N/A 2000-01-01 OBJECTIVES: I. Determine whether plasma choline and breast milk choline levels are low at fasting in a patient with methionine adenosyltransferase deficiency, and if the choline levels are low, determine whether choline levels respond to dietary supplementation with phosphatidylcholine. II. Determine whether this patient has a fatty liver by magnetic resonance spectroscopy.
NCT00006061 ↗ Study of Phosphatidylcholine in a Patient With Methionine Adenosyltransferase Deficiency Completed National Center for Research Resources (NCRR) N/A 2000-01-01 OBJECTIVES: I. Determine whether plasma choline and breast milk choline levels are low at fasting in a patient with methionine adenosyltransferase deficiency, and if the choline levels are low, determine whether choline levels respond to dietary supplementation with phosphatidylcholine. II. Determine whether this patient has a fatty liver by magnetic resonance spectroscopy.
NCT00031135 ↗ Total Parenteral Nutrition-Associated Liver Disease Terminated Northwestern University Phase 2 2001-09-01 This is a study to determine whether choline, when added to total parenteral nutrition (TPN), can help prevent the development of hepatic steatosis, a liver disease, in patients on TPN.
NCT00069550 ↗ Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome Unknown status Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Phase 3 2004-09-01 Rett syndrome (RTT) is a disorder in which the nervous system does not develop properly. RTT generally affects girls, but there are some boys who have been diagnosed with RTT. Symptoms of RTT include small brain size, poor language skills, repetitive hand movements, and seizures. This study will evaluate the effectiveness of two drugs in treating the symptoms of RTT.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Choline C-11

Condition Name

Condition Name for Choline C-11
Intervention Trials
Prostate Cancer 18
Dyslipidemia 5
Hypertriglyceridemia 5
Alzheimer's Disease 5
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Condition MeSH

Condition MeSH for Choline C-11
Intervention Trials
Prostatic Neoplasms 27
Alzheimer Disease 8
Syndrome 6
Dyslipidemias 6
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Clinical Trial Locations for Choline C-11

Trials by Country

Trials by Country for Choline C-11
Location Trials
United States 158
Korea, Republic of 12
Spain 9
United Kingdom 9
France 8
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Trials by US State

Trials by US State for Choline C-11
Location Trials
California 18
Minnesota 10
New Jersey 9
Ohio 9
New York 8
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Clinical Trial Progress for Choline C-11

Clinical Trial Phase

Clinical Trial Phase for Choline C-11
Clinical Trial Phase Trials
Phase 4 25
Phase 3 29
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Choline C-11
Clinical Trial Phase Trials
Completed 77
Unknown status 19
Recruiting 14
[disabled in preview] 40
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Clinical Trial Sponsors for Choline C-11

Sponsor Name

Sponsor Name for Choline C-11
Sponsor Trials
National Cancer Institute (NCI) 17
Essentialis, Inc. 8
National Institutes of Health (NIH) 5
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Sponsor Type

Sponsor Type for Choline C-11
Sponsor Trials
Other 167
Industry 45
NIH 32
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