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Generated: December 14, 2018

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CLINICAL TRIALS PROFILE FOR CHLORHEXIDINE GLUCONATE

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Clinical Trials for Chlorhexidine Gluconate

Trial ID Title Status Sponsor Phase Summary
NCT00002431 The Safety and Effectiveness of Peridex in Preventing or Delaying Fungal Infections of the Mouth in HIV-Infected Patients Completed Procter and Gamble N/A To evaluate the safety and effectiveness of Peridex (an oral rinse containing chlorhexidine gluconate) for preventing the occurrence of clinically-evident microbiologically-documented oral candidiasis in HIV-positive patients, who are at risk of the disease based on previous history of candidiasis.
NCT00123123 Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients Completed National Institute of Dental and Craniofacial Research (NIDCR) Phase 2 Recent studies have found that poor oral hygiene may foster the colonization of the oropharynx by potential respiratory pathogens in mechanically-ventilated (MV), intensive care unit (ICU) patients. Thus, improvements in oral hygiene in MV-ICU patients may prevent ventilator-associated pneumonia (VAP). The specific aims of this investigation are: 1) to organize the necessary infrastructure to develop and perform a pilot clinical trial to evaluate alternative oral hygiene procedures to prevent VAP; 2) to use this organization to perform a pilot clinical trial to determine if the use of oral topical chlorhexidine gluconate (CHX) will prevent dental plaque, oropharyngeal colonization by respiratory pathogens, and VAP in MV-ICU patients.
NCT00123123 Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients Completed State University of New York at Buffalo Phase 2 Recent studies have found that poor oral hygiene may foster the colonization of the oropharynx by potential respiratory pathogens in mechanically-ventilated (MV), intensive care unit (ICU) patients. Thus, improvements in oral hygiene in MV-ICU patients may prevent ventilator-associated pneumonia (VAP). The specific aims of this investigation are: 1) to organize the necessary infrastructure to develop and perform a pilot clinical trial to evaluate alternative oral hygiene procedures to prevent VAP; 2) to use this organization to perform a pilot clinical trial to determine if the use of oral topical chlorhexidine gluconate (CHX) will prevent dental plaque, oropharyngeal colonization by respiratory pathogens, and VAP in MV-ICU patients.
NCT00130221 Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections Completed Centers for Disease Control and Prevention Phase 1 Patients in the intensive care unit are at risk for many infections because the severity of illness and the procedures necessary to care for them. This study is designed to look at a change in bathing procedure as a method to reduce infections. Currently, patients at John H. Stroger Hospital are cleansed with soap and water. However, preliminary data from a previous study at Rush University Medical Center showed that a chlorhexidine (CHG)-impregnated cloth (2% CHG Antiseptic Cloth system, Sage Products, Inc.) decreased skin bacteria and may lessen bacteria in the blood stream. The 2% CHG Antiseptic Cloth system is a non-irritating, no-rinse, cleansing and moisturizing product that contains 2% chlorhexidine gluconate. The goal of this proposed study is to further evaluate the effectiveness of the 2% CHG Antiseptic Cloth system compared with soap and water in cleansing the skin and preventing bacteria from entering the bloodstream.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Chlorhexidine Gluconate

Condition Name

Condition Name for Chlorhexidine Gluconate
Intervention Trials
Surgical Site Infection 7
Bacteremia 5
Healthy 3
Infection 2
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Condition MeSH

Condition MeSH for Chlorhexidine Gluconate
Intervention Trials
Infection 16
Communicable Diseases 13
Surgical Wound Infection 10
Bacteremia 7
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Clinical Trial Locations for Chlorhexidine Gluconate

Trials by Country

Trials by Country for Chlorhexidine Gluconate
Location Trials
United States 77
Canada 7
Israel 4
United Kingdom 3
Mexico 3
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Trials by US State

Trials by US State for Chlorhexidine Gluconate
Location Trials
Michigan 6
Texas 6
Illinois 6
Massachusetts 5
Maryland 5
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Clinical Trial Progress for Chlorhexidine Gluconate

Clinical Trial Phase

Clinical Trial Phase for Chlorhexidine Gluconate
Clinical Trial Phase Trials
Phase 4 26
Phase 3 11
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Chlorhexidine Gluconate
Clinical Trial Phase Trials
Completed 40
Recruiting 27
Not yet recruiting 6
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Clinical Trial Sponsors for Chlorhexidine Gluconate

Sponsor Name

Sponsor Name for Chlorhexidine Gluconate
Sponsor Trials
Medline Industries 6
3M 4
Dexcel Pharma Technologies Ltd. 3
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Sponsor Type

Sponsor Type for Chlorhexidine Gluconate
Sponsor Trials
Other 86
Industry 22
U.S. Fed 4
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Serving hundreds of leading biopharmaceutical companies globally:

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