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Generated: December 18, 2018

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CLINICAL TRIALS PROFILE FOR CHLORAMBUCIL

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Clinical Trials for Chlorambucil

Trial ID Title Status Sponsor Phase Summary
NCT00003421 Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease Completed Medical Research Council Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for advanced Hodgkin's disease. PURPOSE: Randomized phase III trial to compare different combination chemotherapy regimens in treating patients with advanced Hodgkin's disease.
NCT00003617 Chlorambucil Compared With No Further Therapy Following Anti-Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach Unknown status Lymphoma Trials Office Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known whether chlorambucil is more effective than observation in treating low-grade lymphoma of the stomach. PURPOSE: Randomized phase III trial to compare the effectiveness of chlorambucil with that of no further therapy following anti-Helicobacter therapy in treating patients with low-grade lymphoma of the stomach.
NCT00003639 Combination Chemotherapy With or Without Interferon Alfa in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma Unknown status Scotland and Newcastle Lymphoma Group Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Interferon alfa may interfere with the growth of cancer cells and slow the growth of non-Hodgkin's lymphoma. It is not yet known whether combining more than one chemotherapy drug with interferon alfa is more effective than chemotherapy alone in treating patients with low-grade non-Hodgkin's lymphoma. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy with or without interferon alfa in treating patients with low-grade non-Hodgkin's lymphoma.
NCT00004218 Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia Completed Medical Research Council Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for chronic lymphocytic leukemia. PURPOSE: This randomized phase III trial is studying chlorambucil to see how well it works compared to fludarabine and cyclophosphamide or fludarabine alone in treating patients with newly diagnosed chronic lymphocytic leukemia.
NCT00004218 Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia Completed Leukemia Research Fund Phase 3 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for chronic lymphocytic leukemia. PURPOSE: This randomized phase III trial is studying chlorambucil to see how well it works compared to fludarabine and cyclophosphamide or fludarabine alone in treating patients with newly diagnosed chronic lymphocytic leukemia.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Chlorambucil

Condition Name

Condition Name for Chlorambucil
Intervention Trials
Chronic Lymphocytic Leukemia 20
Lymphoma 10
Lymphocytic Leukemia, Chronic 8
Leukemia 4
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Condition MeSH

Condition MeSH for Chlorambucil
Intervention Trials
Leukemia, Lymphoid 41
Leukemia, Lymphocytic, Chronic, B-Cell 41
Leukemia 40
Lymphoma 25
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Clinical Trial Locations for Chlorambucil

Trials by Country

Trials by Country for Chlorambucil
Location Trials
United States 195
Italy 78
United Kingdom 73
Spain 69
Canada 41
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Trials by US State

Trials by US State for Chlorambucil
Location Trials
California 16
Illinois 12
Texas 10
Washington 9
Ohio 9
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Clinical Trial Progress for Chlorambucil

Clinical Trial Phase

Clinical Trial Phase for Chlorambucil
Clinical Trial Phase Trials
Phase 4 2
Phase 3 32
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Chlorambucil
Clinical Trial Phase Trials
Completed 28
Active, not recruiting 14
Recruiting 11
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Clinical Trial Sponsors for Chlorambucil

Sponsor Name

Sponsor Name for Chlorambucil
Sponsor Trials
Hoffmann-La Roche 13
German CLL Study Group 6
Pharmacyclics LLC. 4
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Sponsor Type

Sponsor Type for Chlorambucil
Sponsor Trials
Other 60
Industry 52
NIH 2
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