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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR CHLORAMBUCIL


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All Clinical Trials for Chlorambucil

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003421 ↗ Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease Completed Medical Research Council Phase 3 1998-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for advanced Hodgkin's disease. PURPOSE: Randomized phase III trial to compare different combination chemotherapy regimens in treating patients with advanced Hodgkin's disease.
NCT00003617 ↗ Chlorambucil Compared With No Further Therapy Following Anti-Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach Unknown status Lymphoma Trials Office Phase 3 1995-03-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known whether chlorambucil is more effective than observation in treating low-grade lymphoma of the stomach. PURPOSE: Randomized phase III trial to compare the effectiveness of chlorambucil with that of no further therapy following anti-Helicobacter therapy in treating patients with low-grade lymphoma of the stomach.
NCT00003639 ↗ Combination Chemotherapy With or Without Interferon Alfa in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma Unknown status Scotland and Newcastle Lymphoma Group Phase 3 1993-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Interferon alfa may interfere with the growth of cancer cells and slow the growth of non-Hodgkin's lymphoma. It is not yet known whether combining more than one chemotherapy drug with interferon alfa is more effective than chemotherapy alone in treating patients with low-grade non-Hodgkin's lymphoma. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy with or without interferon alfa in treating patients with low-grade non-Hodgkin's lymphoma.
NCT00004218 ↗ Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia Completed Medical Research Council Phase 3 1999-10-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for chronic lymphocytic leukemia. PURPOSE: This randomized phase III trial is studying chlorambucil to see how well it works compared to fludarabine and cyclophosphamide or fludarabine alone in treating patients with newly diagnosed chronic lymphocytic leukemia.
NCT00004218 ↗ Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia Completed Leukemia Research Fund Phase 3 1999-10-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for chronic lymphocytic leukemia. PURPOSE: This randomized phase III trial is studying chlorambucil to see how well it works compared to fludarabine and cyclophosphamide or fludarabine alone in treating patients with newly diagnosed chronic lymphocytic leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Chlorambucil

Condition Name

Condition Name for Chlorambucil
Intervention Trials
Chronic Lymphocytic Leukemia 23
Lymphoma 10
Lymphocytic Leukemia, Chronic 8
Leukemia 5
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Condition MeSH

Condition MeSH for Chlorambucil
Intervention Trials
Leukemia, Lymphoid 46
Leukemia, Lymphocytic, Chronic, B-Cell 46
Leukemia 46
Lymphoma 27
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Clinical Trial Locations for Chlorambucil

Trials by Country

Trials by Country for Chlorambucil
Location Trials
United States 228
United Kingdom 87
Italy 85
Spain 73
Australia 47
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Trials by US State

Trials by US State for Chlorambucil
Location Trials
California 17
Illinois 13
Texas 11
Washington 10
Kentucky 9
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Clinical Trial Progress for Chlorambucil

Clinical Trial Phase

Clinical Trial Phase for Chlorambucil
Clinical Trial Phase Trials
Phase 4 2
Phase 3 36
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Chlorambucil
Clinical Trial Phase Trials
Completed 41
Active, not recruiting 11
Unknown status 11
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Clinical Trial Sponsors for Chlorambucil

Sponsor Name

Sponsor Name for Chlorambucil
Sponsor Trials
Hoffmann-La Roche 14
German CLL Study Group 8
University of Ulm 4
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Sponsor Type

Sponsor Type for Chlorambucil
Sponsor Trials
Other 82
Industry 71
NIH 3
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