CLINICAL TRIALS PROFILE FOR CEFAZOLIN SODIUM

All Clinical Trials for Cefazolin Sodium

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00867295 ↗	Effectiveness of Antibiotic Prophylaxis for Totally Implantable Venous Access Device	Completed	Istanbul University	Phase 3	2008-09-01	This randomized trial is determining the role of antibiotic prophylaxis in the prevention of the infectious complications in patients carrying out totally implantable venous access device.
NCT01127880 ↗	Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax	Completed	St. Luke's Hospital, Pennsylvania	Phase 2/Phase 3	2005-07-01	The purpose of this study is to examine the efficacy of prophylactic antibiotics in patients with chest tubes for management of thoracic injuries in the reduction of the incidence of empyema as compared to placebo.
NCT01273818 ↗	Effectiveness of Topical Antibiotic Prophylaxis in Inguinal Hernia Repair	Completed	Diskapi Teaching and Research Hospital	Phase 4	2011-01-01	Aim of this study is to measure the effectiveness of topical gentamicin to prevent post-operative infection in inguinal tension-free hernia repair operation.Secondary aim is, if it is effective as a prophylactic agent, to compare it's effect with intra venous single dose cefazolin sodium prophylaxis.
NCT01805856 ↗	Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery	Completed	Ito Hospital	N/A	2010-11-01	The effectiveness of antimicrobial prophylaxis (AMP) for prevention of surgical site infection (SSI) following thyroid and parathyroid surgery remains uncertain. Present prospective randomized control study (Ito-RCT1) assessed the effectiveness of AMP in clean neck surgery associated with thyroid and parathyroid disease.
NCT02017197 ↗	Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil	Completed	Fundação de Amparo à Pesquisa do Estado de São Paulo	Phase 4	2014-08-01	The purpose of this study is to assess whether the switch from branded to generic warfarin or between different generic warfarin tablets may cause fluctuation in the results of coagulation tests (International Normalized Rate, acronym INR) in patients, thus predisposing them to unnecessary risks.
NCT02017197 ↗	Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil	Completed	Federal University of São Paulo	Phase 4	2014-08-01	The purpose of this study is to assess whether the switch from branded to generic warfarin or between different generic warfarin tablets may cause fluctuation in the results of coagulation tests (International Normalized Rate, acronym INR) in patients, thus predisposing them to unnecessary risks.
NCT03226626 ↗	Tumescent Anesthesia Antibiotic Delivery (TAAD)	Not yet recruiting	University of California, Riverside	Phase 2/Phase 3	2021-12-01	This is a multicenter randomized clinical trial (RCT) comparing two modes of antibiotic delivery: Control: Intravenous Antibiotic Delivery (IVAD) Treatment: IVAD + TAAD The Food & Drug Administration (FDA) has approved our Investigational New Drug (IND) application to conduct this RCT. An IND application was necessary because subcutaneous injection of antibiotics in general, and cefazolin and metronidazole in particular are considered to be "off-label". In addition, the tumescent formulation of cefazolin (1gm) and metronidazole (500mg/100ml) in a dilute solution of lidocaine (1gm), epinephrine (1mg) in 100ml and sodium bicarbonate (10mEq/10ml) added a 1000ml bag of 0.9% sodium chloride (total volume 1210ml) is also considered "off-label." This trial will also prospectively study the HK Surgical SubQKath, an over-the-needle subcutaneous catheter specifically designed to deliver relatively large volumes of a relatively dilute TAAD solution. The TAAD trial will document the safety and efficacy of the HK SubQKath

Clinical Trial Conditions for Cefazolin Sodium

Condition Name

Condition Name for Cefazolin Sodium
Intervention	Trials
Surgical Site Infection	2
Sepsis	1
Solid Tumor	1
Thrombosis	1

Condition MeSH

Condition MeSH for Cefazolin Sodium
Intervention	Trials
Surgical Wound Infection	3
Infections	2
Infection	2
Hernia	1

Clinical Trial Locations for Cefazolin Sodium

Trials by Country

Trials by Country for Cefazolin Sodium
Location	Trials
Turkey	2
United States	1
Egypt	1
Brazil	1
Japan	1

Trials by US State

Trials by US State for Cefazolin Sodium
Location	Trials
Pennsylvania	1

Clinical Trial Progress for Cefazolin Sodium

Clinical Trial Phase

Clinical Trial Phase for Cefazolin Sodium
Clinical Trial Phase	Trials
Phase 4	2
Phase 3	1
Phase 2/Phase 3	2

Clinical Trial Status

Clinical Trial Status for Cefazolin Sodium
Clinical Trial Phase	Trials
Completed	6
Not yet recruiting	1
Unknown status	1

Clinical Trial Sponsors for Cefazolin Sodium

Sponsor Name

Sponsor Name for Cefazolin Sodium
Sponsor	Trials
Federal University of São Paulo	1
University of California, Riverside	1
HK Surgical, Inc.	1

Sponsor Type

Sponsor Type for Cefazolin Sodium
Sponsor	Trials
Other	9
Industry	1