CLINICAL TRIALS PROFILE FOR CARBOCAINE
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All Clinical Trials for Carbocaine
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT01981291 ↗ | Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve | Completed | University of Parma | Phase 4 | 2012-10-01 | This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), leads to longer anesthesia and analgesia of the leg. Some reports of accidental intraneural injection mention an extremely long duration. When different drugs and doses were evaluated in a clinical trial of intraneural injection, a longer-than-expected duration was reported. The investigators will compare the two types of injection using the same drug, so as to determine if there is an actual difference in duration. |
| NCT02384915 ↗ | Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy | Completed | ASST Gaetano Pini-CTO | Phase 4 | 2015-01-01 | The aim of the study is to compare the time of home discharge in day-case patients receiving either a spinal anesthesia or a combined sciatic-femoral nerve block for knee arthroscopy |
| NCT02829697 ↗ | The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability | Completed | Innovation Fund Denmark | Phase 4 | 2016-07-01 | The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve and the sciatic nerve in healthy volunteers. The hypothesis is that nerve block duration is correlated to local anaesthetic volume, but only to a certain degree. After a sufficient volume a 'saturation level' will be reached, and nerve block duration will not increase further. |
| NCT02829697 ↗ | The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability | Completed | Nordsjaellands Hospital | Phase 4 | 2016-07-01 | The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve and the sciatic nerve in healthy volunteers. The hypothesis is that nerve block duration is correlated to local anaesthetic volume, but only to a certain degree. After a sufficient volume a 'saturation level' will be reached, and nerve block duration will not increase further. |
| NCT03390426 ↗ | Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension | Completed | Duke University | Phase 4 | 2018-05-03 | The purpose of this prospective randomized double-blind study is to determine if the novel technique of ultrasound guided peri-arterial injection of local anesthetic around the femoral artery decreases ischemic hypertension associated with prolonged lower extremity tourniquet time during total ankle arthroplasty (TAA) and foot fusion surgeries. Patients will be randomized 1:1 to receive either local anesthetic or saline, which will be injected superomedially to the femoral artery in an attempt to block sympathetic afferents and decrease tourniquet associated hypertension intraoperatively. |
| NCT04454203 ↗ | Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension | Recruiting | Duke University | Phase 4 | 2021-02-05 | The goal of this prospective randomized double-blind study is to determine if an ultrasound guided peri-arterial injection of local anesthetic (LA) superomedially the femoral artery via peripheral nerve catheter reverses ischemic hypertension associated with prolonged lower extremity tourniquet time. |
| NCT06047366 ↗ | Combination of Buffered Anesthetic to Treat Mandibular Molars | Recruiting | Indiana University | Phase 4 | 2023-12-05 | The purpose of this study is to determine whether a combination of anesthetics (numbing medicine) will adequately anesthetize teeth over a different combination. A second purpose is to see if the time needed to numb the nerve in a tooth is different between the two anesthetics. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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