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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Queensland Health
QuintilesIMS
Moodys
Covington
UBS
Daiichi Sankyo
Deloitte
Farmers Insurance

Generated: December 16, 2018

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CLINICAL TRIALS PROFILE FOR CARBIDOPA, LEVODOPA AND ENTACAPONE

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Clinical Trials for Carbidopa, Levodopa And Entacapone

Trial ID Title Status Sponsor Phase Summary
NCT00099268 Efficacy and Safety of Carbidopa/Levodopa/Entacapone in Patients With Parkinson's Disease Requiring Initiation of Levodopa Therapy Completed Orion Corporation, Orion Pharma Phase 3 The CELC200A2401 study has been designed in order to evaluate the hypothesis that administering the combination carbidopa/levodopa/entacapone at the time that levodopa therapy is initiated results in a decrease in the risk of the development of motor complications for patients with Parkinson's disease.
NCT00099268 Efficacy and Safety of Carbidopa/Levodopa/Entacapone in Patients With Parkinson's Disease Requiring Initiation of Levodopa Therapy Completed Novartis Pharmaceuticals Phase 3 The CELC200A2401 study has been designed in order to evaluate the hypothesis that administering the combination carbidopa/levodopa/entacapone at the time that levodopa therapy is initiated results in a decrease in the risk of the development of motor complications for patients with Parkinson's disease.
NCT00134966 A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa Completed Novartis Phase 3 The purpose of this study is to achieve approval for the use of carbidopa/levodopa/entacapone in early Parkinson's disease (PD) by demonstrating that when used as initial levodopa therapy in early PD, carbidopa/levodopa/entacapone provides significantly greater symptomatic benefit than immediate release carbidopa/levodopa administered at the same levodopa dosage level of 100 mg three times a day (t.i.d.).
NCT00143026 Study to Compare the Effect of Treatment With Carbidopa/Levodopa/Entacapone on the Quality of Life of Patients With Parkinson's Disease. This Study is Not Recruiting in the United States Completed Novartis Phase 4 This study examines the effect of treatment of levodopa/entacapone on quality of life, as measured by the Parkinson's Disease-Questionnaire 8 (PDQ-8), in Parkinson's disease patients with no or minimal, non-disabling motor fluctuations.
NCT00200447 An Open-Label Feasibility/Pilot Study With [123I]-IBZM SPECT (DOPA-SYN) Completed Molecular NeuroImaging Phase 2 This study conducted to more fully evaluate the way that carbidopa/levodopa and entacapone may work in the brain. This research study uses [123I]-IBZM and dynamic SPECT imaging to determine the amount and the duration of dopamine release from specific regions in the brain after treatment with either the combination of carbidopa/levodopa or the combination of carbidopa/levodopa/entacapone.
NCT00219284 Effects of Carbidopa/Levodopa/Entacapone on Motor Function and Quality of Life in Patients With Parkinson's Disease Completed Novartis Pharmaceuticals Phase 4 To assess motor function and quality of life (QoL) in Parkinson's disease (PD) subjects with end-of-dose wearing off, comparing immediate and delayed switch to carbidopa/levodopa and entacapone.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Carbidopa, Levodopa And Entacapone

Condition Name

Condition Name for Carbidopa, Levodopa And Entacapone
Intervention Trials
Parkinson's Disease 11
Healthy 4
Parkinson Disease 3
Cocaine Abuse 1
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Condition MeSH

Condition MeSH for Carbidopa, Levodopa And Entacapone
Intervention Trials
Parkinson Disease 16
Cocaine-Related Disorders 2
Multiple System Atrophy 1
Narcolepsy 1
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Clinical Trial Locations for Carbidopa, Levodopa And Entacapone

Trials by Country

Trials by Country for Carbidopa, Levodopa And Entacapone
Location Trials
United States 72
Italy 11
Canada 11
Germany 6
Sweden 3
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Trials by US State

Trials by US State for Carbidopa, Levodopa And Entacapone
Location Trials
New York 6
Florida 5
California 5
Texas 4
Pennsylvania 4
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Clinical Trial Progress for Carbidopa, Levodopa And Entacapone

Clinical Trial Phase

Clinical Trial Phase for Carbidopa, Levodopa And Entacapone
Clinical Trial Phase Trials
Phase 4 5
Phase 3 3
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Carbidopa, Levodopa And Entacapone
Clinical Trial Phase Trials
Completed 18
Terminated 2
Recruiting 1
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Clinical Trial Sponsors for Carbidopa, Levodopa And Entacapone

Sponsor Name

Sponsor Name for Carbidopa, Levodopa And Entacapone
Sponsor Trials
Novartis 8
Novartis Pharmaceuticals 3
Orion Corporation, Orion Pharma 3
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Sponsor Type

Sponsor Type for Carbidopa, Levodopa And Entacapone
Sponsor Trials
Industry 18
Other 7
NIH 2
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Serving hundreds of leading biopharmaceutical companies globally:

Julphar
Merck
Johnson and Johnson
US Army
Healthtrust
Queensland Health
Deloitte
Teva
Federal Trade Commission

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