A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of JNJ-28431754 in Patients With Type 2 Diabetes Mellitus
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (ie,
blood levels of JNJ-28431754) and pharmacodynamics (ie, urine and blood levels of glucose) of
JNJ-28431754 compared to placebo in patients with Type 2 diabetes mellitus.
CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride
Janssen Research & Development, LLC
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of
canagliflozin (JNJ-28431754) compared with glimepiride in patients with type 2 diabetes
mellitus with inadequate control despite treatment with metformin.
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