An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes
Completed
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Phase 2
2008-04-01
The purpose of this study is to evaluate the effectiveness, safety, and tolerability of
JNJ-28431754 compared with placebo in patients with type 2 diabetes.
A Study of the Safety and Effectiveness of Canagliflozin (JNJ-28431754) in Promoting Weight Loss in Overweight and Obese Patients Who do Not Have Diabetes
Completed
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Phase 2
2008-05-01
The purpose of this study is to test the safety and effectiveness of JNJ-28431754 in
promoting weight loss in patients who are overweight or obese and who do not have diabetes.
A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of JNJ-28431754 in Patients With Type 2 Diabetes Mellitus
Completed
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Phase 1
2007-06-01
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (ie,
blood levels of JNJ-28431754) and pharmacodynamics (ie, urine and blood levels of glucose) of
JNJ-28431754 compared to placebo in patients with Type 2 diabetes mellitus.
CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride
Completed
Janssen Research & Development, LLC
Phase 3
2009-09-01
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of
canagliflozin (JNJ-28431754) compared with glimepiride in patients with type 2 diabetes
mellitus with inadequate control despite treatment with metformin.
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