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CLINICAL TRIALS PROFILE FOR CALFACTANT

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Clinical Trials for Calfactant

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00506532	The Use of Surfactant in Lung Transplantation: A Randomized Control Pilot Study	Unknown status	Rabin Medical Center	Phase 2/Phase 3	1. Working Hypothesis: The purpose of the trial is to study the effect of exogenous calf surfactant (calfactant) on the prevention of primary graft failure due to ischemic-reperfusion lung injury in lung transplant patients. 2. Aims of the Study: The purpose of the trial is to study the effect of exogenous calf surfactant (calfactant) on the prevention of primary graft failure due to ischemic-reperfusion lung injury in lung transplant patients.
NCT00569530	Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide	Completed	Mallinckrodt	Phase 3	The purpose of this study is to determine if the combination of late doses of Infasurf with inhaled nitric oxide will interact to improve the surfactant function and thus the respiratory status and outcome of treated infants.
NCT00569530	Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide	Completed	ONY	Phase 3	The purpose of this study is to determine if the combination of late doses of Infasurf with inhaled nitric oxide will interact to improve the surfactant function and thus the respiratory status and outcome of treated infants.
NCT00569530	Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide	Completed	University of California, San Francisco	Phase 3	The purpose of this study is to determine if the combination of late doses of Infasurf with inhaled nitric oxide will interact to improve the surfactant function and thus the respiratory status and outcome of treated infants.

Clinical Trial Conditions for Calfactant

Condition Name

Condition Name for Calfactant
Intervention	Trials
Bronchopulmonary Dysplasia	3
Respiratory Distress Syndrome	2
Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction)	1
Acute Lung Injury	1

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Condition MeSH

Condition MeSH for Calfactant
Intervention	Trials
Respiratory Distress Syndrome, Adult	5
Respiratory Distress Syndrome, Newborn	4
Bronchopulmonary Dysplasia	4
Syndrome	2

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Clinical Trial Locations for Calfactant

Trials by Country

Trials by Country for Calfactant
Location	Trials
United States	47
Canada	3
Israel	2
New Zealand	2
Korea, Republic of	1

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Trials by US State

Trials by US State for Calfactant
Location	Trials
New York	5
California	5
Texas	4
Florida	3
Pennsylvania	3

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Clinical Trial Progress for Calfactant

Clinical Trial Phase

Clinical Trial Phase for Calfactant
Clinical Trial Phase	Trials
Phase 3	4
Phase 2/Phase 3	2
Phase 2	1

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Clinical Trial Status

Clinical Trial Status for Calfactant
Clinical Trial Phase	Trials
Completed	4
Unknown status	3
Not yet recruiting	1

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Clinical Trial Sponsors for Calfactant

Sponsor Name

Sponsor Name for Calfactant
Sponsor	Trials
University of California, San Francisco	3
ONY	2
Cystic Fibrosis Foundation Therapeutics	1

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Sponsor Type

Sponsor Type for Calfactant
Sponsor	Trials
Other	15
Industry	3
NIH	1

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