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Last Updated: February 8, 2025

CLINICAL TRIALS PROFILE FOR CALCIUM CHLORIDE; POTASSIUM CHLORIDE; SODIUM CHLORIDE; SODIUM LACTATE


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All Clinical Trials for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00168519 ↗ Contraction (Exercise) Mediated Glucose Uptake as a Therapeutic Target in Type 2 Diabetes Completed Diabetes Australia N/A 2002-10-01 The purpose of this project is to determine whether glucose metabolism can be improved by administering a substance (nitric oxide donor) normally released by muscles during exercise.
NCT00168519 ↗ Contraction (Exercise) Mediated Glucose Uptake as a Therapeutic Target in Type 2 Diabetes Completed Hoffmann-La Roche N/A 2002-10-01 The purpose of this project is to determine whether glucose metabolism can be improved by administering a substance (nitric oxide donor) normally released by muscles during exercise.
NCT00168519 ↗ Contraction (Exercise) Mediated Glucose Uptake as a Therapeutic Target in Type 2 Diabetes Completed National Health and Medical Research Council, Australia N/A 2002-10-01 The purpose of this project is to determine whether glucose metabolism can be improved by administering a substance (nitric oxide donor) normally released by muscles during exercise.
NCT00168519 ↗ Contraction (Exercise) Mediated Glucose Uptake as a Therapeutic Target in Type 2 Diabetes Completed Baker Heart Research Institute N/A 2002-10-01 The purpose of this project is to determine whether glucose metabolism can be improved by administering a substance (nitric oxide donor) normally released by muscles during exercise.
NCT00279617 ↗ Levetiracetam Treatment of Panic Disorder and Lactate-Induced Panic Attacks Completed UCB Pharma Phase 3 2006-01-01 The main purpose of this research study is to determine whether the drug Levetiracetam (Keppra™) is effective in the prevention of panic attacks. The drug Levetiracetam (Keppra™) has been approved for the treatment of seizures by the U.S. Federal Food and Drug Administration (FDA) and is available by prescription. Levetiracetam has not been approved by the FDA for the treatment of panic disorder.
NCT00279617 ↗ Levetiracetam Treatment of Panic Disorder and Lactate-Induced Panic Attacks Completed University of Cincinnati Phase 3 2006-01-01 The main purpose of this research study is to determine whether the drug Levetiracetam (Keppra™) is effective in the prevention of panic attacks. The drug Levetiracetam (Keppra™) has been approved for the treatment of seizures by the U.S. Federal Food and Drug Administration (FDA) and is available by prescription. Levetiracetam has not been approved by the FDA for the treatment of panic disorder.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate

Condition Name

Condition Name for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Intervention Trials
Lactate 3
Septic Shock 3
Hyperlactatemia 3
Covid19 2
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Condition MeSH

Condition MeSH for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Intervention Trials
Shock 8
Wounds and Injuries 5
Brain Injuries 5
Shock, Septic 4
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Clinical Trial Locations for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate

Trials by Country

Trials by Country for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Location Trials
United States 14
France 6
Indonesia 5
Moldova, Republic of 4
Egypt 4
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Trials by US State

Trials by US State for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Location Trials
California 3
Utah 1
Pennsylvania 1
New Mexico 1
Florida 1
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Clinical Trial Progress for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate

Clinical Trial Phase

Clinical Trial Phase for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Clinical Trial Phase Trials
Phase 4 23
Phase 3 15
Phase 2/Phase 3 4
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Clinical Trial Status

Clinical Trial Status for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Clinical Trial Phase Trials
Completed 34
Not yet recruiting 14
Recruiting 11
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Clinical Trial Sponsors for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate

Sponsor Name

Sponsor Name for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Sponsor Trials
Innogene Kalbiotech Pte. Ltd 5
Yuria-Pharm 4
Institut d'Anesthesiologie des Alpes Maritimes 3
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Sponsor Type

Sponsor Type for Calcium Chloride; Potassium Chloride; Sodium Chloride; Sodium Lactate
Sponsor Trials
Other 85
Industry 20
NIH 1
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Clinical Trials, Market Analysis, and Projections for Calcium Chloride, Potassium Chloride, and Sodium Lactate

Introduction

This article delves into the current clinical trials, market analysis, and future projections for three significant compounds: calcium chloride, potassium chloride, and sodium lactate. These substances are crucial in various medical, agricultural, and industrial applications.

Calcium Chloride

Clinical Trials

Calcium chloride has been the subject of several clinical trials, particularly in the context of medical emergencies and surgical procedures.

Hyperkalemia-Induced Cardiac Arrest

A recent study published in PubMed evaluated the efficacy of calcium chloride and sodium bicarbonate in treating hyperkalemia-induced cardiac arrest in a pig model. The results showed that while sodium bicarbonate significantly increased the number of animals achieving return of spontaneous circulation (ROSC) and reduced the time to ROSC, calcium chloride had no significant effect on these outcomes[4].

Bioequivalence and Pharmacokinetics

Another study focused on the bioequivalence and pharmacokinetics of intravenous calcium chloride and calcium gluconate. This randomized controlled trial found that the dose ratio of calcium gluconate to calcium chloride was 3.11, and both compounds had identical time courses in terms of serum ionized calcium concentration after adjusting for the dose ratio[5].

Market Analysis

Calcium chloride is used in various industries, including medicine, food, and construction. However, specific market data for calcium chloride is less readily available compared to other compounds.

Medical Applications

In the medical sector, calcium chloride is used as a calcium supplement and in emergency treatments for conditions like hyperkalemia. Its use in these areas is critical but does not drive large-scale market growth compared to other sectors.

Projections

While there is no comprehensive market projection specifically for calcium chloride, its continued use in medical and other applications ensures a stable demand. However, the market size and growth rate are not as significant as those of other compounds like potassium chloride.

Potassium Chloride

Clinical Trials

Potassium chloride is often used in medical applications, particularly in electrolyte replacement therapies and cardiac treatments.

Electrolyte Replacement

In clinical settings, potassium chloride is used to treat potassium deficiencies and in cardiac arrest scenarios. However, specific recent clinical trials focusing solely on potassium chloride are not as prominent as those involving its use in broader therapeutic contexts.

Market Analysis

The potassium chloride market is robust and growing, driven by several key factors.

Agricultural Sector

The primary driver of the potassium chloride market is the increasing global food demand. Farmers use potassium chloride as a key fertilizer to enhance crop yield and quality, as potassium is essential for plant growth and nutrient absorption. The market size was valued at $727.05 million in 2024 and is projected to reach $1.018 billion by 2031, growing at a CAGR of 4.30% from 2024 to 2031[2].

Pharmaceutical Sector

The pharmaceutical industry is also a significant driver, with potassium chloride used in electrolyte replacement therapies and cardiac treatments. The increased prevalence of chronic diseases and an aging population further boost demand in this sector[2].

Projections

The potassium chloride market is expected to continue its growth trajectory, driven by both agricultural and pharmaceutical demands. The projected CAGR of 4.30% from 2024 to 2031 indicates a strong and stable market future.

Sodium Lactate

Clinical Trials

Sodium lactate is used in various medical applications, including resuscitation fluids and as a component in parenteral nutrition.

Medical Applications

While specific recent clinical trials on sodium lactate are limited, its use in medical settings is well-established. It is often part of broader studies on resuscitation fluids and parenteral nutrition.

Market Analysis

The sodium lactate market is dynamic and influenced by several factors.

Market Size and Growth

The sodium lactate market was valued at $0.315 billion in 2022 and is projected to grow to $0.656 billion by 2032, exhibiting a CAGR of 8.50% during the forecast period (2023-2032). The growing R&D expenditures and the expanding pharmaceutical industry are key drivers of this market growth[3].

Pharmaceutical Industry

The pharmaceutical sector is a major consumer of sodium lactate, using it in various formulations and treatments. The increasing demand for pharmaceutical products, especially those involving parenteral nutrition and resuscitation fluids, drives the market forward[3].

Projections

The sodium lactate market is expected to grow significantly, driven by the pharmaceutical industry's expansion and increasing R&D expenditures. The projected CAGR of 8.50% from 2023 to 2032 indicates a robust growth trajectory.

Key Takeaways

  • Calcium Chloride: While it has specific medical applications, its market size and growth are not as significant as those of potassium chloride or sodium lactate. Clinical trials highlight its limited efficacy in certain emergency treatments.
  • Potassium Chloride: The market is driven by agricultural and pharmaceutical demands, with a projected CAGR of 4.30% from 2024 to 2031. It is essential for crop yield and quality and for electrolyte replacement therapies.
  • Sodium Lactate: The market is growing at a CAGR of 8.50% from 2023 to 2032, driven by the pharmaceutical industry and increasing R&D expenditures. It is crucial in medical applications such as parenteral nutrition and resuscitation fluids.

FAQs

What are the primary uses of calcium chloride in medical settings?

Calcium chloride is used as a calcium supplement and in emergency treatments for conditions like hyperkalemia.

How does the agricultural sector impact the potassium chloride market?

The agricultural sector drives the potassium chloride market by using it as a key fertilizer to enhance crop yield and quality, addressing the increasing global food demand.

What is the projected growth rate of the sodium lactate market?

The sodium lactate market is projected to grow at a CAGR of 8.50% from 2023 to 2032, driven by the expanding pharmaceutical industry and increasing R&D expenditures.

What are the key drivers of the potassium chloride market?

The key drivers include the increasing global food demand and the growing pharmaceutical industry, particularly for electrolyte replacement therapies and cardiac treatments.

How does sodium lactate contribute to medical treatments?

Sodium lactate is used in medical settings as part of resuscitation fluids and parenteral nutrition, contributing to patient care and recovery.

Sources

  1. Calcium Chloride Hydrate - Drug Targets, Indications, Patents. Synapse.
  2. Potassium Chloride Market Size, Share, Trends & Forecast. Verified Market Research.
  3. Sodium Lactate Market Analysis | Market Research Future. Market Research Future.
  4. Sodium Bicarbonate and Calcium Chloride for the ... - PubMed. PubMed.
  5. Bioequivalence and Pharmacokinetics of Intravenous Calcium .... PubMed.

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