CLINICAL TRIALS PROFILE FOR BYFAVO
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All Clinical Trials for Byfavo
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT05201300 ↗ | Remimazolam and Propofol Anesthesia in Elderly Patients | Not yet recruiting | Ajou University School of Medicine | N/A | 2022-02-01 | Remimazolam is a recently developed ultra-short agonist acting at the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)A receptor. Remimazolam has a combination of the hemodynamic stability of benzodiazepines and the advantages of propofol, such as rapid onset, short duration of action, and improved controllability. A recent study showed that the efficacy of two induction doses of remimazolam (6 and 12 mg/kg/h) as a sedative for general anesthesia was not inferior to propofol (2.0-2.5 mg/kg), and hemodynamically more stable. On the other hand, a study on the emergence time and quality between propofol and remimazolam showed inconsistent results. The purpose of this study is to compare remimazolam to propofol on the intraoperative hemodynamic changes and recovery profiles, when used in combination with remifentanil in elderly patients undergoing general anesthesia. |
| NCT05412914 ↗ | Remimazolam and Propofol on the Left Ventricular Strain During Anesthesia Induction for Non-cardiac Surgery | Not yet recruiting | Konkuk University Medical Center | Phase 4 | 2022-08-01 | This study to compare the impacts of remimazolam or propofol on the left ventricular global longitudinal strain (LV-GLS) during anesthesia induction for non-cardiac surgery. LV-GLS is analyzed by using speckle tracking technique of transthoracic echocardiography. |
| NCT05835713 ↗ | Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam | Not yet recruiting | Samsung Medical Center | N/A | 2023-05-01 | Rigid bronchoscopy usually requires deep general anesthesia, but the duration of the procedure is relatively short. Remimazolam, a recently developed anesthetics, showed faster recovery from anesthesia and stable hemodynamics compared to propofol, the most popular anesthetics. However, few studies have investigated the usefulness of remimazolam for rigid bronchoscopy. Therefore, the investigators compared the usefulness of propofol and remimazolam in total intravenous anesthesia for rigid bronchoscopy. |
| NCT05866315 ↗ | The Effect of Remimazolam on Opioid Induced Hyperalgesia | Recruiting | Wonkwang University Hospital | N/A | 2023-05-19 | The goal of this prospective, randomized, controlled study is to investigate the effect of remimazolam on opioid-induced hyperalgesia (OIH) in patients undergoing single port-laparoscopically assisted urologic surgery. The main question[s] it aims to answer are: - [The mechanical hyperalgesia threshold] - [Area of hyperalgesia around the surgical incision 24 h after surgery (cm^2)] In three groups: Group RHR (Remimazolam- High-dose Remifentanil), Group DHR (Desflurane-low-dose Remifentanil) or Group DLR (Control). |
| NCT05907525 ↗ | Effect of Sevoflurane and Remimazolam on Arterial Oxygenation During One-lung Ventilation | Recruiting | Pusan National University Yangsan Hospital | N/A | 2023-06-29 | The goal of this clinical trial is to compare the effect of sevoflurane and remimazolam on arterial oxygenation during one lung ventilation in patients undergoing video-assisted thoracoscopic surgery. |
| NCT05975255 ↗ | Dose Finding Study for Remimazolam in Children | Recruiting | Seoul National University Hospital | Phase 2 | 2023-11-16 | This study aims to find effective dose of remimazolam for inducing loss of consciousness in children aged 2 to 8 years old. We will explore ED90 of remimazolam for loss of consciousness in 2 minutes after intravenous injection, via a up-and-down method with biased-coin design. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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