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Last Updated: January 19, 2022

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CLINICAL TRIALS PROFILE FOR BUSULFEX

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All Clinical Trials for Busulfex

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00002831 ↗	Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous or Acute Leukemia	Completed	National Cancer Institute (NCI)	Phase 1/Phase 2	1995-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase I/II trial to study the effectiveness of high-dose chemotherapy plus peripheral stem cell transplantation in treating patients with chronic myelogenous or acute leukemia.
NCT00002831 ↗	Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous or Acute Leukemia	Completed	M.D. Anderson Cancer Center	Phase 1/Phase 2	1995-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase I/II trial to study the effectiveness of high-dose chemotherapy plus peripheral stem cell transplantation in treating patients with chronic myelogenous or acute leukemia.
NCT00003926 ↗	Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors	Terminated	Masonic Cancer Center, University of Minnesota	Phase 1	1998-11-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of high-dose chemotherapy. PURPOSE: Phase I trial to study the effectiveness of amifostine in protecting from the side effects of peripheral stem cell transplantation in treating patients who have high-risk or relapsed solid tumors.
NCT00004088 ↗	Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple Myeloma	Completed	National Cancer Institute (NCI)	Phase 2	1999-04-13	RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies, such as interferon alfa, use different ways to stimulate the immune system and stop cancer cells from growing. Thalidomide may stop the growth of cancer cells by stopping blood flow to the tumor. Pamidronate may help to reduce the side effects of treatment for multiple myeloma. PURPOSE: This phase II trial is studying combination chemotherapy, peripheral stem cell transplantation, biological therapy, pamidronate, and thalidomide to see how well they work in treating patients with stage I, stage II, or stage III multiple myeloma.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for Busulfex

Condition Name

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Condition Name for Busulfex
Intervention	Trials
Leukemia	33
Myelodysplastic Syndrome	24
Lymphoma	21
Acute Myeloid Leukemia	16
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Condition MeSH

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Condition MeSH for Busulfex
Intervention	Trials
Leukemia	59
Myelodysplastic Syndromes	39
Preleukemia	38
Leukemia, Myeloid	37
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Clinical Trial Locations for Busulfex

Trials by Country

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Trials by Country for Busulfex
Location	Trials
United States	308
Canada	19
Korea, Republic of	4
Israel	2
Australia	1
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Trials by US State

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Trials by US State for Busulfex
Location	Trials
Texas	54
New York	17
Minnesota	17
Massachusetts	14
California	13
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Clinical Trial Progress for Busulfex

Clinical Trial Phase

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Clinical Trial Phase for Busulfex
Clinical Trial Phase	Trials
Phase 3	7
Phase 2/Phase 3	5
Phase 2	76
[disabled in preview]	21
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Clinical Trial Status

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Clinical Trial Status for Busulfex
Clinical Trial Phase	Trials
Completed	57
Recruiting	29
Terminated	24
[disabled in preview]	13
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Clinical Trial Sponsors for Busulfex

Sponsor Name

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Sponsor Name for Busulfex
Sponsor	Trials
M.D. Anderson Cancer Center	47
National Cancer Institute (NCI)	42
Masonic Cancer Center, University of Minnesota	14
[disabled in preview]	8
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Sponsor Type

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Sponsor Type for Busulfex
Sponsor	Trials
Other	172
NIH	50
Industry	24
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