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Last Updated: April 19, 2024

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CLINICAL TRIALS PROFILE FOR BRUKINSA

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All Clinical Trials for Brukinsa

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT03145064 ↗	Study of BTK Inhibitor Zanubrutinib in Participants With Relapsed/Refractory Non-GCB Type Diffuse Large B Cell Lymphoma	Completed	BeiGene	Phase 2	2017-06-30	Screening (up to 28 days); daily treatment until disease progression, unacceptable toxicity or death, withdrawal of consent, lost to follow-up, or study termination from sponsor; treatment (up to 2 years), safety follow-up (30 days); survival follow-up until data cutoff for final analysis.
NCT03332017 ↗	A Study Comparing Obinutuzumab and BGB-3111 Versus Obinutuzumab Alone in Treating R/R Follicular Lymphoma	Active, not recruiting	BeiGene	Phase 2	2017-11-15	The purpose of the study is to evaluate the efficacy, safety and tolerability and of BGB-3111 plus obinutuzumab versus obinutuzumab alone in participants with relapsed/refractory non-Hodgkin follicular lymphoma.
NCT03336333 ↗	A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL	Recruiting	BeiGene	Phase 3	2017-11-02	To compare efficacy between zanubrutinib versus bendamustine and rituximab in patients with previously untreated CLL/SLL, as measured by progression free survival.
NCT04002297 ↗	Study Comparing Zanubrutinib + Rituximab Versus Bendamustine + Rituximab in Participants With Untreated Mantle Cell Lymphoma	Recruiting	BeiGene	Phase 3	2019-08-21	This is a randomized study to compare the efficacy and safety of zanubrutinib plus rituximab versus bendamustine plus rituximab in previously untreated participants with mantle cell lymphoma (MCL) who are not eligible for stem cell transplantation.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for Brukinsa

Condition Name

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Condition Name for Brukinsa
Intervention	Trials
Small Lymphocytic Lymphoma	3
Chronic Lymphocytic Leukemia	2
Chronic Lymphocytic Leukemia (CLL)	2
Healthy Volunteers	2
[disabled in preview]	0
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Condition MeSH

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Condition MeSH for Brukinsa
Intervention	Trials
Lymphoma	17
Lymphoma, B-Cell	7
Leukemia, Lymphoid	7
Leukemia, Lymphocytic, Chronic, B-Cell	7
[disabled in preview]	0
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Clinical Trial Locations for Brukinsa

Trials by Country

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Trials by Country for Brukinsa
Location	Trials
United States	92
China	27
Australia	22
France	14
Japan	11
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Trials by US State

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Trials by US State for Brukinsa
Location	Trials
Texas	7
Florida	6
Illinois	6
New York	5
Nevada	5
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Clinical Trial Progress for Brukinsa

Clinical Trial Phase

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Clinical Trial Phase for Brukinsa
Clinical Trial Phase	Trials
Phase 3	5
Phase 2/Phase 3	1
Phase 2	15
[disabled in preview]	5
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Clinical Trial Status

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Clinical Trial Status for Brukinsa
Clinical Trial Phase	Trials
Not yet recruiting	11
Recruiting	10
Completed	3
[disabled in preview]	1
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Clinical Trial Sponsors for Brukinsa

Sponsor Name

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Sponsor Name for Brukinsa
Sponsor	Trials
BeiGene	17
National Cancer Institute (NCI)	4
Peking Union Medical College Hospital	2
[disabled in preview]	1
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Sponsor Type

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Sponsor Type for Brukinsa
Sponsor	Trials
Industry	21
Other	13
NIH	4
[disabled in preview]	0
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