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Last Updated: December 12, 2024

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CLINICAL TRIALS PROFILE FOR BRUKINSA


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All Clinical Trials for Brukinsa

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03145064 ↗ Study of BTK Inhibitor Zanubrutinib in Participants With Relapsed/Refractory Non-GCB Type Diffuse Large B Cell Lymphoma Completed BeiGene Phase 2 2017-06-30 Screening (up to 28 days); daily treatment until disease progression, unacceptable toxicity or death, withdrawal of consent, lost to follow-up, or study termination from sponsor; treatment (up to 2 years), safety follow-up (30 days); survival follow-up until data cutoff for final analysis.
NCT03332017 ↗ A Study Comparing Obinutuzumab and BGB-3111 Versus Obinutuzumab Alone in Treating R/R Follicular Lymphoma Active, not recruiting BeiGene Phase 2 2017-11-15 The purpose of the study is to evaluate the efficacy, safety and tolerability and of BGB-3111 plus obinutuzumab versus obinutuzumab alone in participants with relapsed/refractory non-Hodgkin follicular lymphoma.
NCT03336333 ↗ A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL Recruiting BeiGene Phase 3 2017-11-02 To compare efficacy between zanubrutinib versus bendamustine and rituximab in patients with previously untreated CLL/SLL, as measured by progression free survival.
NCT04002297 ↗ Study Comparing Zanubrutinib + Rituximab Versus Bendamustine + Rituximab in Participants With Untreated Mantle Cell Lymphoma Recruiting BeiGene Phase 3 2019-08-21 This is a randomized study to compare the efficacy and safety of zanubrutinib plus rituximab versus bendamustine plus rituximab in previously untreated participants with mantle cell lymphoma (MCL) who are not eligible for stem cell transplantation.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Brukinsa

Condition Name

Condition Name for Brukinsa
Intervention Trials
Small Lymphocytic Lymphoma 3
Recurrent Transformed B-Cell Non-Hodgkin Lymphoma 2
Refractory Transformed B-cell Non-Hodgkin Lymphoma 2
Diffuse Large B-cell Lymphoma 2
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Condition MeSH

Condition MeSH for Brukinsa
Intervention Trials
Lymphoma 17
Lymphoma, B-Cell 7
Leukemia, Lymphoid 7
Leukemia, Lymphocytic, Chronic, B-Cell 7
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Clinical Trial Locations for Brukinsa

Trials by Country

Trials by Country for Brukinsa
Location Trials
United States 92
China 27
Australia 22
France 14
Japan 11
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Trials by US State

Trials by US State for Brukinsa
Location Trials
Texas 7
Florida 6
Illinois 6
New York 5
Nevada 5
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Clinical Trial Progress for Brukinsa

Clinical Trial Phase

Clinical Trial Phase for Brukinsa
Clinical Trial Phase Trials
Phase 3 5
Phase 2/Phase 3 1
Phase 2 16
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Clinical Trial Status

Clinical Trial Status for Brukinsa
Clinical Trial Phase Trials
Not yet recruiting 12
Recruiting 10
Completed 3
[disabled in preview] 1
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Clinical Trial Sponsors for Brukinsa

Sponsor Name

Sponsor Name for Brukinsa
Sponsor Trials
BeiGene 17
National Cancer Institute (NCI) 4
Peking Union Medical College Hospital 2
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Sponsor Type

Sponsor Type for Brukinsa
Sponsor Trials
Industry 21
Other 14
NIH 4
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