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Generated: March 24, 2019

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CLINICAL TRIALS PROFILE FOR BETA CAROTENE

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Clinical Trials for Beta Carotene

Trial ID Title Status Sponsor Phase Summary
NCT00000152 Randomized Trial of Beta-Carotene and Macular Degeneration Unknown status National Eye Institute (NEI) Phase 3 To determine whether 50 mg of beta-carotene taken every other day reduces the risk of developing age-related macular degeneration (AMD) among male U.S. physicians who were aged 40 to 84 in 1982. To investigate the possible relationship of AMD with other antioxidants, including selenium and vitamins A, C, and E. To identify potential risk factors for development of AMD. Possible risk factors include height, systemic hypertension, cardiovascular disease, blood cholesterol, cigarette smoking, iris and skin color, sunlight exposure, body mass index, diabetes, and alcohol intake.
NCT00000157 Randomized Trial of Aspirin and Cataracts in U.S. Physicians Terminated National Eye Institute (NEI) Phase 3 To determine whether 325 mg of aspirin taken on -alternate days reduces the risk of developing cataract among male U.S. physicians who were aged 40 to 84 in 1982. To identify potential risk factors for cataract development, such as age, blood pressure, blood cholesterol, height, diabetes, medication use, and history of previous eye trauma or surgery.
NCT00000161 Randomized Trials of Vitamin Supplements and Eye Disease Unknown status National Eye Institute (NEI) Phase 3 To determine whether vitamin E supplementation reduces the risk of cataract and age-related macular degeneration (AMD) in women. To determine whether vitamin C supplementation reduces the risk of cataract and AMD in women. To determine whether beta-carotene supplementation reduces the risk of cataract and AMD in women. To determine whether alternate day, low-dose aspirin reduces the risk of cataract and AMD in women. To identify potential risk factors for cataract and AMD including cigarette smoking, alcohol intake, blood pressure, blood cholesterol, cardiovascular disease, height, body mass index, and diabetes.
NCT00000500 Physicians' Health Study Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To assess the effect on cardiovascular mortality of alternate-day consumption of 325 milligrams of aspirin and, secondarily, the effect on cancer incidence of alternate-day consumption of 50 milligrams of beta-carotene.
NCT00000500 Physicians' Health Study Completed Brigham and Women's Hospital Phase 3 To assess the effect on cardiovascular mortality of alternate-day consumption of 325 milligrams of aspirin and, secondarily, the effect on cancer incidence of alternate-day consumption of 50 milligrams of beta-carotene.
NCT00000539 Arterial Disease Multifactorial Intervention Trial (ADMIT) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To evaluate, in asymptomatic and symptomatic participants with peripheral arterial disease, the feasibility of recruitment and adherence, efficacy and safety of HDL-C raising along with effective control of LDL-C levels, antioxidant therapy, antithrombotic therapy, and their combinations.
NCT00000541 Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 2 To determine if supplements of vitamin C, vitamin E, beta-carotene, and B-vitamins (a combination of folic acid, vitamins B6 and B12) reduce risk of major cardiovascular events in high risk women with a prior history of atherosclerotic cardiovascular disease. The trial is a companion to the Women's Health Study (WHS), a primary prevention trial of vitamin E and aspirin in a low risk population of women.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Beta Carotene

Condition Name

Condition Name for Beta Carotene
Intervention Trials
Heart Diseases 4
Cardiovascular Diseases 4
Myocardial Ischemia 3
Cataract 3
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Condition MeSH

Condition MeSH for Beta Carotene
Intervention Trials
Cataract 4
Macular Degeneration 4
Heart Diseases 4
Cardiovascular Diseases 4
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Clinical Trial Locations for Beta Carotene

Trials by Country

Trials by Country for Beta Carotene
Location Trials
United States 53
United Kingdom 2
Israel 2
Iran, Islamic Republic of 2
Germany 2
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Trials by US State

Trials by US State for Beta Carotene
Location Trials
Florida 3
Texas 3
New York 3
Massachusetts 3
Maryland 3
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Clinical Trial Progress for Beta Carotene

Clinical Trial Phase

Clinical Trial Phase for Beta Carotene
Clinical Trial Phase Trials
Phase 4 3
Phase 3 14
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Beta Carotene
Clinical Trial Phase Trials
Completed 16
Unknown status 5
Recruiting 5
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Clinical Trial Sponsors for Beta Carotene

Sponsor Name

Sponsor Name for Beta Carotene
Sponsor Trials
National Heart, Lung, and Blood Institute (NHLBI) 5
National Eye Institute (NEI) 5
National Cancer Institute (NCI) 2
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Sponsor Type

Sponsor Type for Beta Carotene
Sponsor Trials
Other 38
NIH 15
Industry 7
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