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CLINICAL TRIALS PROFILE FOR BESIVANCE

All Clinical Trials for Besivance

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00347932 ↗	A Study to Determine if 0.6% ISV-403 is Safe and Effective in the Treatment of Bacterial Conjunctivitis.	Completed	Bausch & Lomb Incorporated	Phase 3	2006-06-01	Evaluation of the clinical and microbial efficacy of 0.6% ISV-403, compared to vehicle in the treatment of bacterial conjunctivitis.
NCT00824070 ↗	Assessment of the Concentrations of Besifloxacin, Moxifloxacin, or Gatifloxacin in the Aqueous Humor of Subjects	Completed	Bausch & Lomb Incorporated	Phase 1	2009-02-01	This study is being conducted to assess the concentration of besifloxacin, moxifloxacin, or gatifloxacin in aqueous humor samples collected following topical instillation of the associated formulation in subjects undergoing cataract surgery.
NCT00905762 ↗	Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After Topical Instillation	Completed	Bausch & Lomb Incorporated	Phase 1	2009-03-01	The purpose of this study is to assess the concentration of besifloxacin compared to gatifloxacin and moxifloxacin in human conjunctival tissue, following a single drop of the drug instilled topically into the study eye. Conjunctival biopsies will be performed at specified time points, followed by the use of loteprednol etabonate/tobramycin ophthalmic suspension four times a day for 5 days.
NCT00924729 ↗	Study of Ocular Penetration of Topically Administered Fluoroquinolones	Completed	Johns Hopkins University	Phase 4	2009-09-01	This study is being conducted to evaluate the intraocular penetration of Moxifloxacin 0.5% ophthalmic solution (Vigamox) and Besifloxacin 0.6% ophthalmic suspension (Besivance) after pre-operative topical administration in subjects undergoing cataract surgery.

Clinical Trial Conditions for Besivance

Condition Name

Condition Name for Besivance
Intervention	Trials
Bacterial Conjunctivitis	4
Cataract Extraction	2
Dry Eye Syndromes	1
Healthy	1

Condition MeSH

Condition MeSH for Besivance
Intervention	Trials
Conjunctivitis, Bacterial	5
Conjunctivitis	5
Cataract	4
Keratoconjunctivitis Sicca	1

Clinical Trial Locations for Besivance

Trials by Country

Trials by Country for Besivance
Location	Trials
United States	12

Trials by US State

Trials by US State for Besivance
Location	Trials
New York	6
New Jersey	2
Kentucky	1
Missouri	1
Pennsylvania	1

Clinical Trial Progress for Besivance

Clinical Trial Phase

Clinical Trial Phase for Besivance
Clinical Trial Phase	Trials
Phase 4	5
Phase 3	4
Phase 2/Phase 3	1

Clinical Trial Status

Clinical Trial Status for Besivance
Clinical Trial Phase	Trials
Completed	10
Terminated	2
Recruiting	1

Clinical Trial Sponsors for Besivance

Sponsor Name

Sponsor Name for Besivance
Sponsor	Trials
Bausch & Lomb Incorporated	10
John, George, M.D.	1
Ocular Therapeutix, Inc.	1

Sponsor Type

Sponsor Type for Besivance
Sponsor	Trials
Industry	12
Other	7